Sulfamerazine

DERMATOLOGICALS

Key facts

Sulfamerazine is an ofm drug catalogued in DrugCentral. It was first approved by the FDA in 1949. DrugCentral lists 1 molecular target, including folP.

• Approval status: ofm (first approved 1949 by the FDA).
• Molecular targets: folP (1 listed in DrugCentral).
• ATC code: D06BA06 (Sulfonamides).
• Molecular formula: C11H12N4O2S; molecular weight 264.30 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Contraindications (8)

• Anemia due to enzyme deficiency
• Breastfeeding (mother)
• Disease of blood AND/OR blood-forming organ
• Disease of liver
• Kidney disease
• Megaloblastic anemia due to folate deficiency
• Porphyria
• Third trimester pregnancy

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Dihydropteroate synthase	folP	inhibitor	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1949-08-16	FDA	—	LEDERLE

ATC classification

ATC code	Therapeutic hierarchy
D06BA06	DERMATOLOGICALS › ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE › CHEMOTHERAPEUTICS FOR TOPICAL USE › Sulfonamides
J01ED07	ANTIINFECTIVES FOR SYSTEMIC USE › ANTIBACTERIALS FOR SYSTEMIC USE › SULFONAMIDES AND TRIMETHOPRIM › Long-acting sulfonamides
J01EE07	ANTIINFECTIVES FOR SYSTEMIC USE › ANTIBACTERIALS FOR SYSTEMIC USE › SULFONAMIDES AND TRIMETHOPRIM › Combinations of sulfonamides and trimethoprim, incl. derivatives

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Sulfamerazine is on its molecule page.

• Molecular formula: C₁₁H₁₂N₄O₂S
• Molecular weight: 264.30 g/mol
• CAS number: 127-79-7
• InChIKey: QPPBRPIAZZHUNT-UHFFFAOYSA-N
• PubChem CID: 5325

CC1=CC=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=N1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Sulfamerazine work?

Its molecular targets in DrugCentral include folP (inhibitor).

When was Sulfamerazine first approved?

Sulfamerazine was first approved by the FDA in 1949.

What is the chemical formula of Sulfamerazine?

Sulfamerazine has the molecular formula C11H12N4O2S and a molecular weight of 264.30 g/mol.

Sources

• DrugCentral drug card 2510 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL438 — compound record and bioactivity
• PubChem CID 5325 — chemical identifiers
• DrugBank DB01581 — drug record
• FDA UNII UR1SAB295F — substance identity
• DailyMed: FDA labels for Sulfamerazine — current prescribing information (label search)

How this page is built: methodology · editorial policy & corrections.