6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide

C12H8ClF2N3O2 — CID 103186812

IUPAC6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide
SMILESO=C(Nc1ccc(OC(F)F)cc1)c1cncc(Cl)n1
InChIInChI=1S/C12H8ClF2N3O2/c13-10-6-16-5-9(18-10)11(19)17-7-1-3-8(4-2-7)20-12(14)15/h1-6,12H,(H,17,19)
InChIKeyYYJWOOOTHXVIAC-UHFFFAOYSA-N
MW299.66 g/mol
LogP2.98
Rot. Bonds4

About 6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide

6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide (PubChem CID 103186812) has the molecular formula C12H8ClF2N3O2 and a molecular weight of 299.66 g/mol. Its IUPAC name is 6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide.

Molecular Properties

Compound Name6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide
PubChem CID103186812
Molecular FormulaC12H8ClF2N3O2
Molecular Weight299.66 g/mol
Exact Mass299.03
IUPAC Name6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide
SMILESO=C(Nc1ccc(OC(F)F)cc1)c1cncc(Cl)n1
InChIInChI=1S/C12H8ClF2N3O2/c13-10-6-16-5-9(18-10)11(19)17-7-1-3-8(4-2-7)20-12(14)15/h1-6,12H,(H,17,19)
InChIKeyYYJWOOOTHXVIAC-UHFFFAOYSA-N
XLogP2.98
TPSA64.11 Ų
H-Bond Donors1
H-Bond Acceptors4
Rotatable Bonds4
Heavy Atoms20
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500299.66
LogP ≤ 52.98
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 104

Analyze 6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

6-chloro-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazine-2-carboxamide
CID 106551160
5-bromo-N-[4-(difluoromethoxy)phenyl]pyridine-2-carboxamide
CID 62953190
N-[4-(difluoromethoxy)phenyl]-5-methylpyrazine-2-carboxamide
CID 2447949
6-chloro-N-(6-chloro-3-pyridinyl)pyrazine-2-carboxamide
CID 103186985
6-chloro-N-(3-chloro-4-propan-2-yloxyphenyl)pyrazine-2-carboxamide
CID 106551049
1,3-bis[4-(difluoromethoxy)phenyl]urea
CID 11537485
2-chloro-N-[4-(difluoromethoxy)phenyl]-5-hydroxybenzamide
CID 106501367
6-chloro-N-(1H-indol-5-yl)pyrazine-2-carboxamide
CID 103186986
N-[4-(difluoromethoxy)phenyl]-1-methyl-6-oxopyridazine-3-carboxamide
CID 7941086
N-(4-acetamidophenyl)-4-(difluoromethoxy)benzamide
CID 2168312
4-[[4-(difluoromethoxy)benzoyl]amino]benzamide
CID 842852
N-[4-(difluoromethoxy)phenyl]-2,3-difluoropyridine-4-carboxamide
CID 105380332

Frequently Asked Questions

What is the IUPAC name of 6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide?
The IUPAC name of 6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide (CID 103186812) is 6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide.
What is the SMILES notation for 6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide?
The canonical SMILES for 6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide is O=C(Nc1ccc(OC(F)F)cc1)c1cncc(Cl)n1.
What is the InChIKey of 6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide?
The InChIKey is YYJWOOOTHXVIAC-UHFFFAOYSA-N. The full InChI is InChI=1S/C12H8ClF2N3O2/c13-10-6-16-5-9(18-10)11(19)17-7-1-3-8(4-2-7)20-12(14)15/h1-6,12H,(H,17,19).
What are the key properties of 6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide?
6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide has a molecular weight of 299.66 g/mol, XLogP of 2.98, 4 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 6-chloro-N-[4-(difluoromethoxy)phenyl]pyrazine-2-carboxamide is sourced from PubChem (CID 103186812), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).