5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide

C18H22N4O5 — CID 109276725

IUPAC5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide
SMILESCOc1cc(NC(=O)c2cnc(N3CCOCC3)cn2)cc(OC)c1OC
InChIInChI=1S/C18H22N4O5/c1-24-14-8-12(9-15(25-2)17(14)26-3)21-18(23)13-10-20-16(11-19-13)22-4-6-27-7-5-22/h8-11H,4-7H2,1-3H3,(H,21,23)
InChIKeyJPGWPVQXNBNFDJ-UHFFFAOYSA-N
MW374.40 g/mol
LogP1.59
Rot. Bonds6

About 5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide

5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide (PubChem CID 109276725) has the molecular formula C18H22N4O5 and a molecular weight of 374.40 g/mol. Its IUPAC name is 5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide.

Molecular Properties

Compound Name5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide
PubChem CID109276725
Molecular FormulaC18H22N4O5
Molecular Weight374.40 g/mol
Exact Mass374.16
IUPAC Name5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide
SMILESCOc1cc(NC(=O)c2cnc(N3CCOCC3)cn2)cc(OC)c1OC
InChIInChI=1S/C18H22N4O5/c1-24-14-8-12(9-15(25-2)17(14)26-3)21-18(23)13-10-20-16(11-19-13)22-4-6-27-7-5-22/h8-11H,4-7H2,1-3H3,(H,21,23)
InChIKeyJPGWPVQXNBNFDJ-UHFFFAOYSA-N
XLogP1.59
TPSA95.04 Ų
H-Bond Donors1
H-Bond Acceptors8
Rotatable Bonds6
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500374.40
LogP ≤ 51.59
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 108

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Related Compounds

2-(3,4,5-Trimethoxyphenylamino)-6-(4-acetamidophenyl-oxy)-pyrazine
CID 24879264
N2-(pyridin-4-yl)-N6-(3,4,5-trimethoxyphenyl)pyrazine-2,6-diamine
CID 24879390
3-[4-(4-Methylpiperazin-1-yl)anilino]-5-[3-(prop-2-enoylamino)phenoxy]pyrazine-2-carboxamide
CID 71667665
N-[3-({6-[(3,4,5-trimethoxyphenyl)amino]pyrazin-2-yl}amino)phenyl]acetamide
CID 24879143
6-(Pyridin-3-yloxy)-N-(3,4,5-trimethoxyphenyl)pyrazin-2-amine
CID 24879206
N-[4-({6-[(3,4,5-trimethoxyphenyl)amino]pyrazin-2-yl}amino)phenyl]acetamide
CID 24879331
6-(Pyridin-4-yloxy)-N-(3,4,5-trimethoxyphenyl)pyrazin-2-amine
CID 24879394
2-(3,4,5-Trimethoxyphenylamino)-6-(3-acetamidophenyl-oxy)-pyrazine
CID 24879529
6-(4-pyridin-2-ylpiperazin-1-yl)-N-(3,4,5-trimethoxyphenyl)pyrimidine-4-carboxamide
CID 155558000
3-(Piperidin-1-YL)-N-(3,4,5-trimethoxyphenyl)quinoxaline-2-carboxamide
CID 15990398
1-(Pyrazin-2-YL)-N-(3,4,5-trimethoxyphenyl)piperidine-4-carboxamide
CID 23609712
2-(4-pyridin-2-ylpiperazin-1-yl)-N-(3,4,5-trimethoxyphenyl)acetamide
CID 4267660

Frequently Asked Questions

What is the IUPAC name of 5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide?
The IUPAC name of 5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide (CID 109276725) is 5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide.
What is the SMILES notation for 5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide?
The canonical SMILES for 5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide is COc1cc(NC(=O)c2cnc(N3CCOCC3)cn2)cc(OC)c1OC.
What is the InChIKey of 5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide?
The InChIKey is JPGWPVQXNBNFDJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H22N4O5/c1-24-14-8-12(9-15(25-2)17(14)26-3)21-18(23)13-10-20-16(11-19-13)22-4-6-27-7-5-22/h8-11H,4-7H2,1-3H3,(H,21,23).
What are the key properties of 5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide?
5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide has a molecular weight of 374.40 g/mol, XLogP of 1.59, 6 rotatable bonds, 1 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for 5-morpholin-4-yl-N-(3,4,5-trimethoxyphenyl)pyrazine-2-carboxamide is sourced from PubChem (CID 109276725), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).