2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide

C18H19F2NO3 — CID 111334767

IUPAC2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide
SMILESCC(O)(CNC(=O)Cc1cccc(OC(F)F)c1)c1ccccc1
InChIInChI=1S/C18H19F2NO3/c1-18(23,14-7-3-2-4-8-14)12-21-16(22)11-13-6-5-9-15(10-13)24-17(19)20/h2-10,17,23H,11-12H2,1H3,(H,21,22)
InChIKeyKPZUOFUKZSRLNT-UHFFFAOYSA-N
MW335.35 g/mol
LogP2.85
Rot. Bonds7

About 2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide

2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide (PubChem CID 111334767) has the molecular formula C18H19F2NO3 and a molecular weight of 335.35 g/mol. Its IUPAC name is 2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide.

Molecular Properties

Compound Name2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide
PubChem CID111334767
Molecular FormulaC18H19F2NO3
Molecular Weight335.35 g/mol
Exact Mass335.13
IUPAC Name2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide
SMILESCC(O)(CNC(=O)Cc1cccc(OC(F)F)c1)c1ccccc1
InChIInChI=1S/C18H19F2NO3/c1-18(23,14-7-3-2-4-8-14)12-21-16(22)11-13-6-5-9-15(10-13)24-17(19)20/h2-10,17,23H,11-12H2,1H3,(H,21,22)
InChIKeyKPZUOFUKZSRLNT-UHFFFAOYSA-N
XLogP2.85
TPSA58.56 Ų
H-Bond Donors2
H-Bond Acceptors3
Rotatable Bonds7
Heavy Atoms24
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500335.35
LogP ≤ 52.85
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 103

Analyze 2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

2-[3-(difluoromethoxy)phenyl]-N-[2-(3-fluorophenyl)-2-methylpropyl]acetamide
CID 86971523
N-(2-hydroxy-2-phenylpropyl)-2-naphthalen-2-ylacetamide
CID 111335174
2-[4-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-methylpropyl)acetamide
CID 65109978
N-(2-amino-2-methylpropyl)-2-(3-propan-2-yloxyphenyl)acetamide;hydrochloride
CID 119626689
2-(4-chlorophenyl)-N-(2-hydroxy-2-phenylpropyl)acetamide
CID 110663977
2-[3-(2-phenylpropan-2-yloxy)phenyl]acetic acid
CID 69488903
3-(difluoromethoxy)-N-(2-hydroxy-2-phenylpropyl)thiophene-2-carboxamide
CID 111519591
1-(2-hydroxy-2-phenylpropyl)-3-[1-(3-methoxyphenyl)propan-2-yl]urea
CID 111334657
2-[4-(difluoromethoxy)phenyl]-N-(1,1-diphenylethyl)acetamide
CID 56522955
3-hydroxy-N-(2-hydroxy-2-phenylpropyl)-3-phenylbutanamide
CID 110025392
2-[4-(difluoromethoxy)phenyl]-N-[(3-methoxyphenyl)methyl]acetamide
CID 32734290
1-amino-2-[3-(difluoromethoxy)phenyl]propan-2-ol
CID 107105450

Frequently Asked Questions

What is the IUPAC name of 2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide?
The IUPAC name of 2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide (CID 111334767) is 2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide.
What is the SMILES notation for 2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide?
The canonical SMILES for 2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide is CC(O)(CNC(=O)Cc1cccc(OC(F)F)c1)c1ccccc1.
What is the InChIKey of 2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide?
The InChIKey is KPZUOFUKZSRLNT-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H19F2NO3/c1-18(23,14-7-3-2-4-8-14)12-21-16(22)11-13-6-5-9-15(10-13)24-17(19)20/h2-10,17,23H,11-12H2,1H3,(H,21,22).
What are the key properties of 2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide?
2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide has a molecular weight of 335.35 g/mol, XLogP of 2.85, 7 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[3-(difluoromethoxy)phenyl]-N-(2-hydroxy-2-phenylpropyl)acetamide is sourced from PubChem (CID 111334767), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).