6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine

C19H12F5N5 — CID 118095116

IUPAC6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
SMILESCc1nc2c(F)cc(F)cn2c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1
InChIInChI=1S/C19H12F5N5/c1-10-17(29-9-12(20)6-14(21)18(29)26-10)15-7-25-8-16(28-15)27-13-4-2-11(3-5-13)19(22,23)24/h2-9H,1H3,(H,27,28)
InChIKeyZNKYAEWNBUGYIX-UHFFFAOYSA-N
MW405.33 g/mol
LogP5.14
Rot. Bonds3

About 6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine

6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine (PubChem CID 118095116) has the molecular formula C19H12F5N5 and a molecular weight of 405.33 g/mol. Its IUPAC name is 6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine.

Molecular Properties

Compound Name6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
PubChem CID118095116
Molecular FormulaC19H12F5N5
Molecular Weight405.33 g/mol
Exact Mass405.10
IUPAC Name6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
SMILESCc1nc2c(F)cc(F)cn2c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1
InChIInChI=1S/C19H12F5N5/c1-10-17(29-9-12(20)6-14(21)18(29)26-10)15-7-25-8-16(28-15)27-13-4-2-11(3-5-13)19(22,23)24/h2-9H,1H3,(H,27,28)
InChIKeyZNKYAEWNBUGYIX-UHFFFAOYSA-N
XLogP5.14
TPSA55.11 Ų
H-Bond Donors1
H-Bond Acceptors5
Rotatable Bonds3
Heavy Atoms29
Complexity—

Lipinski Rule of Five

1 violation

RuleValue
MW ≤ 500405.33
LogP ≤ 55.14
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 105

Analyze 6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine with MolForge

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Related Compounds

6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
CID 159805438
3-(6-chloropyrazin-2-yl)-6,8-difluoro-2-methylimidazo[1,2-a]pyridine
CID 118101491
6-(6-fluoro-2-methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
CID 122578372
6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
CID 118094690
6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-4-nitro-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine
CID 122578371
N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine
CID 118095018
6-[2-(methylideneamino)-3-[(Z)-prop-1-enyl]-5-(trifluoromethyl)imidazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
CID 144848728
6-(5,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
CID 73427235
6-(2-cyclobutyl-6-fluorobenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[2-(difluoromethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[2-(difluoromethyl)-6-fluorobenzimidazol-1-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-(2,6,8-trimethylimidazo[1,2-a]pyrazin-3-yl)pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-(2,6,8-trimethylimidazo[1,2-a]pyrazin-3-yl)pyrazin-2-amine
CID 159072528
6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
CID 118094327
6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine
CID 118094686
6-(2-ethyl-6-fluorobenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
CID 118095108

Frequently Asked Questions

What is the IUPAC name of 6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine?
The IUPAC name of 6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine (CID 118095116) is 6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine.
What is the SMILES notation for 6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine?
The canonical SMILES for 6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine is Cc1nc2c(F)cc(F)cn2c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.
What is the InChIKey of 6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine?
The InChIKey is ZNKYAEWNBUGYIX-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H12F5N5/c1-10-17(29-9-12(20)6-14(21)18(29)26-10)15-7-25-8-16(28-15)27-13-4-2-11(3-5-13)19(22,23)24/h2-9H,1H3,(H,27,28).
What are the key properties of 6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine?
6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine has a molecular weight of 405.33 g/mol, XLogP of 5.14, 3 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 6-(6,8-difluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine is sourced from PubChem (CID 118095116), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).