2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide

C6H5F3N2O2S — CID 118831789

IUPAC2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide
SMILESNS(=O)(=O)c1ccnc(C(F)F)c1F
InChIInChI=1S/C6H5F3N2O2S/c7-4-3(14(10,12)13)1-2-11-5(4)6(8)9/h1-2,6H,(H2,10,12,13)
InChIKeyOOUPRIXWMNDTJG-UHFFFAOYSA-N
MW226.18 g/mol
LogP0.81
Rot. Bonds2

About 2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide

2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide (PubChem CID 118831789) has the molecular formula C6H5F3N2O2S and a molecular weight of 226.18 g/mol. Its IUPAC name is 2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide.

Molecular Properties

Compound Name2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide
PubChem CID118831789
Molecular FormulaC6H5F3N2O2S
Molecular Weight226.18 g/mol
Exact Mass226.00
IUPAC Name2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide
SMILESNS(=O)(=O)c1ccnc(C(F)F)c1F
InChIInChI=1S/C6H5F3N2O2S/c7-4-3(14(10,12)13)1-2-11-5(4)6(8)9/h1-2,6H,(H2,10,12,13)
InChIKeyOOUPRIXWMNDTJG-UHFFFAOYSA-N
XLogP0.81
TPSA73.05 Ų
H-Bond Donors1
H-Bond Acceptors3
Rotatable Bonds2
Heavy Atoms14
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500226.18
LogP ≤ 50.81
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 103

Analyze 2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

6-(difluoromethyl)-4-fluoro-5-methylpyridine-3-sulfonamide
CID 118854245
2-(difluoromethyl)-5-fluoropyridine-3-sulfonamide
CID 118854230
2-(difluoromethyl)-3-(trifluoromethyl)pyridine-4-sulfonyl chloride
CID 118832290
2-(difluoromethyl)-6-methylpyridine-3-sulfonamide
CID 118848789
5-bromo-2-(difluoromethyl)pyridine-3-sulfonamide
CID 130095356
2-(difluoromethyl)-3-fluoro-4-propan-2-ylpyridine
CID 139525099
2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide
CID 118848760
6-cyano-5-(difluoromethyl)-4-fluoropyridine-3-sulfonamide
CID 119012791
4-amino-6-(difluoromethyl)-5-methylpyridine-3-sulfonamide
CID 118800250
4-amino-5-chloro-6-(difluoromethyl)pyridine-3-sulfonamide
CID 118817790
6-(difluoromethyl)-5-hydroxypyridine-2-sulfonamide
CID 118809083
ethyl 2-[2-(difluoromethyl)-3-fluoro-4-pyridinyl]acetate
CID 133091163

Frequently Asked Questions

What is the IUPAC name of 2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide?
The IUPAC name of 2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide (CID 118831789) is 2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide.
What is the SMILES notation for 2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide?
The canonical SMILES for 2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide is NS(=O)(=O)c1ccnc(C(F)F)c1F.
What is the InChIKey of 2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide?
The InChIKey is OOUPRIXWMNDTJG-UHFFFAOYSA-N. The full InChI is InChI=1S/C6H5F3N2O2S/c7-4-3(14(10,12)13)1-2-11-5(4)6(8)9/h1-2,6H,(H2,10,12,13).
What are the key properties of 2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide?
2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide has a molecular weight of 226.18 g/mol, XLogP of 0.81, 2 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(difluoromethyl)-3-fluoropyridine-4-sulfonamide is sourced from PubChem (CID 118831789), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).