2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide

C6H6F2N2O3S — CID 118848760

IUPAC2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide
SMILESNS(=O)(=O)c1cc(O)cnc1C(F)F
InChIInChI=1S/C6H6F2N2O3S/c7-6(8)5-4(14(9,12)13)1-3(11)2-10-5/h1-2,6,11H,(H2,9,12,13)
InChIKeyJGPLAODHKOKIOO-UHFFFAOYSA-N
MW224.19 g/mol
LogP0.37
Rot. Bonds2

About 2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide

2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide (PubChem CID 118848760) has the molecular formula C6H6F2N2O3S and a molecular weight of 224.19 g/mol. Its IUPAC name is 2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide.

Molecular Properties

Compound Name2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide
PubChem CID118848760
Molecular FormulaC6H6F2N2O3S
Molecular Weight224.19 g/mol
Exact Mass224.01
IUPAC Name2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide
SMILESNS(=O)(=O)c1cc(O)cnc1C(F)F
InChIInChI=1S/C6H6F2N2O3S/c7-6(8)5-4(14(9,12)13)1-3(11)2-10-5/h1-2,6,11H,(H2,9,12,13)
InChIKeyJGPLAODHKOKIOO-UHFFFAOYSA-N
XLogP0.37
TPSA93.28 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds2
Heavy Atoms14
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500224.19
LogP ≤ 50.37
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

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Related Compounds

2-(difluoromethyl)-5-fluoropyridine-3-sulfonamide
CID 118854230
5-bromo-2-(difluoromethyl)pyridine-3-sulfonamide
CID 130095356
5-(bromomethyl)-6-(difluoromethyl)pyridin-3-ol
CID 130097039
4-amino-6-(difluoromethyl)-5-methylpyridine-3-sulfonamide
CID 118800250
6-(difluoromethyl)-4-fluoro-5-methylpyridine-3-sulfonamide
CID 118854245
4-amino-5-chloro-6-(difluoromethyl)pyridine-3-sulfonamide
CID 118817790
6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide
CID 130072903
5-bromo-2-(difluoromethyl)pyridine-4-sulfonamide
CID 130095357
5-amino-6-bromo-2-(difluoromethyl)pyridine-3-sulfonamide
CID 130102347
5-chloro-6-(difluoromethyl)-4-methoxypyridine-3-sulfonamide
CID 134686410
5-cyano-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide
CID 130077095
5-chloro-2-(difluoromethyl)pyridine-3-sulfonyl chloride
CID 130095757

Frequently Asked Questions

What is the IUPAC name of 2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide?
The IUPAC name of 2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide (CID 118848760) is 2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide.
What is the SMILES notation for 2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide?
The canonical SMILES for 2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide is NS(=O)(=O)c1cc(O)cnc1C(F)F.
What is the InChIKey of 2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide?
The InChIKey is JGPLAODHKOKIOO-UHFFFAOYSA-N. The full InChI is InChI=1S/C6H6F2N2O3S/c7-6(8)5-4(14(9,12)13)1-3(11)2-10-5/h1-2,6,11H,(H2,9,12,13).
What are the key properties of 2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide?
2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide has a molecular weight of 224.19 g/mol, XLogP of 0.37, 2 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide is sourced from PubChem (CID 118848760), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).