6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide

C6H5ClF2N2O3S — CID 130072903

IUPAC6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide
SMILESNS(=O)(=O)c1cc(Cl)nc(C(F)F)c1O
InChIInChI=1S/C6H5ClF2N2O3S/c7-3-1-2(15(10,13)14)5(12)4(11-3)6(8)9/h1,6,12H,(H2,10,13,14)
InChIKeyCIXMLYHRPYEQOV-UHFFFAOYSA-N
MW258.63 g/mol
LogP1.03
Rot. Bonds2

About 6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide

6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide (PubChem CID 130072903) has the molecular formula C6H5ClF2N2O3S and a molecular weight of 258.63 g/mol. Its IUPAC name is 6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide.

Molecular Properties

Compound Name6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide
PubChem CID130072903
Molecular FormulaC6H5ClF2N2O3S
Molecular Weight258.63 g/mol
Exact Mass257.97
IUPAC Name6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide
SMILESNS(=O)(=O)c1cc(Cl)nc(C(F)F)c1O
InChIInChI=1S/C6H5ClF2N2O3S/c7-3-1-2(15(10,13)14)5(12)4(11-3)6(8)9/h1,6,12H,(H2,10,13,14)
InChIKeyCIXMLYHRPYEQOV-UHFFFAOYSA-N
XLogP1.03
TPSA93.28 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds2
Heavy Atoms15
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500258.63
LogP ≤ 51.03
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

Computed Properties (RDKit)

Structural Alerts{'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Analyze 6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

6-chloro-2-(difluoromethyl)-4-iodopyridine-3-sulfonamide
CID 130073584
6-chloro-2-(difluoromethyl)-3-iodopyridine-4-sulfonyl chloride
CID 130073549
6-chloro-4-cyano-2-(difluoromethyl)pyridine-3-sulfonamide
CID 130071480
3-chloro-2-(difluoromethyl)-6-methylpyridine-4-sulfonamide
CID 134674571
3-chloro-2-(difluoromethyl)-6-iodopyridine-4-sulfonamide
CID 130073590
2-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide
CID 118848760
6-(difluoromethyl)-5-hydroxypyridine-2-sulfonamide
CID 118809083
5-chloro-2-cyano-6-(difluoromethyl)pyridine-3-sulfonamide
CID 134685410
5-bromo-2-(difluoromethyl)pyridine-3-sulfonamide
CID 130095356
5-amino-6-bromo-2-(difluoromethyl)pyridine-3-sulfonamide
CID 130102347
5-amino-2-cyano-6-(difluoromethyl)pyridine-3-sulfonamide
CID 130103775
3,4-dibromo-6-chloro-2-(difluoromethyl)pyridine
CID 130098856

Frequently Asked Questions

What is the IUPAC name of 6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide?
The IUPAC name of 6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide (CID 130072903) is 6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide.
What is the SMILES notation for 6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide?
The canonical SMILES for 6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide is NS(=O)(=O)c1cc(Cl)nc(C(F)F)c1O.
What is the InChIKey of 6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide?
The InChIKey is CIXMLYHRPYEQOV-UHFFFAOYSA-N. The full InChI is InChI=1S/C6H5ClF2N2O3S/c7-3-1-2(15(10,13)14)5(12)4(11-3)6(8)9/h1,6,12H,(H2,10,13,14).
What are the key properties of 6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide?
6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide has a molecular weight of 258.63 g/mol, XLogP of 1.03, 2 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 6-chloro-2-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide is sourced from PubChem (CID 130072903), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).