5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine

C8H8ClF3N2 — CID 130639761

IUPAC5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine
SMILESCC(F)(F)CNc1ncc(Cl)cc1F
InChIInChI=1S/C8H8ClF3N2/c1-8(11,12)4-14-7-6(10)2-5(9)3-13-7/h2-3H,4H2,1H3,(H,13,14)
InChIKeySAFGYJADGHTHJS-UHFFFAOYSA-N
MW224.61 g/mol
LogP2.94
Rot. Bonds3

About 5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine

5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine (PubChem CID 130639761) has the molecular formula C8H8ClF3N2 and a molecular weight of 224.61 g/mol. Its IUPAC name is 5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine.

Molecular Properties

Compound Name5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine
PubChem CID130639761
Molecular FormulaC8H8ClF3N2
Molecular Weight224.61 g/mol
Exact Mass224.03
IUPAC Name5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine
SMILESCC(F)(F)CNc1ncc(Cl)cc1F
InChIInChI=1S/C8H8ClF3N2/c1-8(11,12)4-14-7-6(10)2-5(9)3-13-7/h2-3H,4H2,1H3,(H,13,14)
InChIKeySAFGYJADGHTHJS-UHFFFAOYSA-N
XLogP2.94
TPSA24.92 Ų
H-Bond Donors1
H-Bond Acceptors2
Rotatable Bonds3
Heavy Atoms14
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500224.61
LogP ≤ 52.94
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 102

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Related Compounds

1-N-(5-chloro-3-fluoro-2-pyridinyl)-2-methylpropane-1,2-diamine
CID 79867421
5-chloro-3-fluoro-N-(2-methoxy-2-methylpropyl)pyridin-2-amine
CID 115681787
5-chloro-3-fluoro-N-(2-fluoroethyl)pyridin-2-amine
CID 130478073
5-chloro-3-fluoro-N-(2-methylsulfanylethyl)pyridin-2-amine
CID 79728558
1-N-(5-chloro-3-fluoro-2-pyridinyl)-3-methylbutane-1,2-diamine
CID 79728261
5-chloro-3-fluoro-N-[(2-methylcyclopropyl)methyl]pyridin-2-amine
CID 115681742
2-[(5-chloro-3-fluoro-2-pyridinyl)amino]acetamide
CID 79727822
2-N-(5-chloro-3-fluoro-2-pyridinyl)-2-methylbutane-1,2-diamine
CID 79734278
5-chloro-3-fluoro-N-(5-methylsulfanylpentyl)pyridin-2-amine
CID 104925521
2-N-(5-chloro-3-fluoro-2-pyridinyl)-2,3-dimethylbutane-1,2-diamine
CID 115311005
2-[(5-chloro-3-fluoro-2-pyridinyl)amino]-N-propan-2-ylacetamide
CID 79727927
4-[[(5-chloro-3-fluoro-2-pyridinyl)amino]methyl]phenol
CID 113252113

Frequently Asked Questions

What is the IUPAC name of 5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine?
The IUPAC name of 5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine (CID 130639761) is 5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine.
What is the SMILES notation for 5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine?
The canonical SMILES for 5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine is CC(F)(F)CNc1ncc(Cl)cc1F.
What is the InChIKey of 5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine?
The InChIKey is SAFGYJADGHTHJS-UHFFFAOYSA-N. The full InChI is InChI=1S/C8H8ClF3N2/c1-8(11,12)4-14-7-6(10)2-5(9)3-13-7/h2-3H,4H2,1H3,(H,13,14).
What are the key properties of 5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine?
5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine has a molecular weight of 224.61 g/mol, XLogP of 2.94, 3 rotatable bonds, 1 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for 5-chloro-N-(2,2-difluoropropyl)-3-fluoropyridin-2-amine is sourced from PubChem (CID 130639761), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).