2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine

C74H92F6N18O — CID 145424638

About 2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine

2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine (PubChem CID 145424638) has the molecular formula C74H92F6N18O and a molecular weight of 1363.66 g/mol. Its IUPAC name is 2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine.

Molecular Properties

• Compound Name: 2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine
• PubChem CID: 145424638
• Molecular Formula: C74H92F6N18O
• Molecular Weight: 1363.66 g/mol
• Exact Mass: 1362.76
• IUPAC Name: 2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine
• SMILES: CN1CCN(c2cccc3nc(C4CCCC(c5ncccc5C(F)(F)F)N4C)cn23)CC1.CN1CCN(c2cccc3nc(C4CCCC(c5ncccc5C5CC5)N4C)cn23)CC1.CN1CCN(c2cccc3nc(C4CCCC(c5ncccc5OC(F)(F)F)N4C)cn23)CC1
• InChI: InChI=1S/C26H34N6.C24H29F3N6O.C24H29F3N6/c1-29-14-16-31(17-15-29)25-10-4-9-24-28-21(18-32(24)25)22-7-3-8-23(30(22)2)26-20(19-11-12-19)6-5-13-27-26;1-30-12-14-32(15-13-30)22-10-4-9-21-29-17(16-33(21)22)18-6-3-7-19(31(18)2)23-20(8-5-11-28-23)34-24(25,26)27;1-30-12-14-32(15-13-30)22-10-4-9-21-29-18(16-33(21)22)19-7-3-8-20(31(19)2)23-17(24(25,26)27)6-5-11-28-23/h4-6,9-10,13,18-19,22-23H,3,7-8,11-12,14-17H2,1-2H3;4-5,8-11,16,18-19H,3,6-7,12-15H2,1-2H3;4-6,9-11,16,19-20H,3,7-8,12-15H2,1-2H3
• InChIKey: WTKZIGFBGZFUOS-UHFFFAOYSA-N
• XLogP: 12.93
• TPSA: 128.96 Ų
• H-Bond Acceptors: 19
• Rotatable Bonds: 11
• Heavy Atoms: 99
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1363.66
LogP ≤ 5	12.93
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	19

Frequently Asked Questions

What is the IUPAC name of 2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine?

The IUPAC name of 2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine (CID 145424638) is 2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine.

What is the SMILES notation for 2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine?

The canonical SMILES for 2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine is CN1CCN(c2cccc3nc(C4CCCC(c5ncccc5C(F)(F)F)N4C)cn23)CC1.CN1CCN(c2cccc3nc(C4CCCC(c5ncccc5C5CC5)N4C)cn23)CC1.CN1CCN(c2cccc3nc(C4CCCC(c5ncccc5OC(F)(F)F)N4C)cn23)CC1.

What is the InChIKey of 2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine?

The InChIKey is WTKZIGFBGZFUOS-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H34N6.C24H29F3N6O.C24H29F3N6/c1-29-14-16-31(17-15-29)25-10-4-9-24-28-21(18-32(24)25)22-7-3-8-23(30(22)2)26-20(19-11-12-19)6-5-13-27-26;1-30-12-14-32(15-13-30)22-10-4-9-21-29-17(16-33(21)22)18-6-3-7-19(31(18)2)23-20(8-5-11-28-23)34-24(25,26)27;1-30-12-14-32(15-13-30)22-10-4-9-21-29-18(16-33(21)22)19-7-3-8-20(31(19)2)23-17(24(25,26)27)6-5-11-28-23/h4-6,9-10,13,18-19,22-23H,3,7-8,11-12,14-17H2,1-2H3;4-5,8-11,16,18-19H,3,6-7,12-15H2,1-2H3;4-6,9-11,16,19-20H,3,7-8,12-15H2,1-2H3.

What are the key properties of 2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine?

2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine has a molecular weight of 1363.66 g/mol, XLogP of 12.93, 11 rotatable bonds, 0 hydrogen bond donors, and 19 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[6-(3-cyclopropyl-2-pyridinyl)-1-methylpiperidin-2-yl]-5-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethoxy)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine;5-(4-methylpiperazin-1-yl)-2-[1-methyl-6-[3-(trifluoromethyl)-2-pyridinyl]piperidin-2-yl]imidazo[1,2-a]pyridine is sourced from PubChem (CID 145424638), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).