6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine

C26H28N8 — CID 148617941

IUPAC6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine
SMILESCC(C)N1CCN(c2ccc(Nc3nc(-c4ccc5c(c4)CN=C5)cn4ccnc34)cn2)CC1
InChIInChI=1S/C26H28N8/c1-18(2)32-9-11-33(12-10-32)24-6-5-22(16-29-24)30-25-26-28-7-8-34(26)17-23(31-25)19-3-4-20-14-27-15-21(20)13-19/h3-8,13-14,16-18H,9-12,15H2,1-2H3,(H,30,31)
InChIKeyNFRHGQMVKYJSPY-UHFFFAOYSA-N
MW452.57 g/mol
LogP4.00
Rot. Bonds5

About 6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine

6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine (PubChem CID 148617941) has the molecular formula C26H28N8 and a molecular weight of 452.57 g/mol. Its IUPAC name is 6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine.

Molecular Properties

Compound Name6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine
PubChem CID148617941
Molecular FormulaC26H28N8
Molecular Weight452.57 g/mol
Exact Mass452.24
IUPAC Name6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine
SMILESCC(C)N1CCN(c2ccc(Nc3nc(-c4ccc5c(c4)CN=C5)cn4ccnc34)cn2)CC1
InChIInChI=1S/C26H28N8/c1-18(2)32-9-11-33(12-10-32)24-6-5-22(16-29-24)30-25-26-28-7-8-34(26)17-23(31-25)19-3-4-20-14-27-15-21(20)13-19/h3-8,13-14,16-18H,9-12,15H2,1-2H3,(H,30,31)
InChIKeyNFRHGQMVKYJSPY-UHFFFAOYSA-N
XLogP4.00
TPSA73.95 Ų
H-Bond Donors1
H-Bond Acceptors8
Rotatable Bonds5
Heavy Atoms34
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500452.57
LogP ≤ 54.00
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 108

Analyze 6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine with MolForge

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Related Compounds

N-[6-(3,3-dimethylazetidin-1-yl)-3-pyridinyl]-6-(3H-isoindol-5-yl)imidazo[1,2-a]pyrazin-8-amine
CID 158104617
6-(3H-isoindol-5-yl)-N-(4-piperazin-1-ylphenyl)imidazo[1,2-a]pyrazin-8-amine
CID 147798212
N-[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]-6-(3H-isoindol-5-yl)imidazo[1,2-a]pyrazin-8-amine
CID 158104618
6-(3H-isoindol-5-yl)-N-[3-methoxy-4-(2-methoxyethoxy)phenyl]imidazo[1,2-a]pyrazin-8-amine
CID 147310764
N-(6-morpholin-4-yl-3-pyridinyl)-6-quinazolin-6-ylimidazo[1,2-a]pyrazin-8-amine
CID 141271386
1-(3-hydroxy-3-methylazetidin-1-yl)-2-[4-[[6-(3H-isoindol-5-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenoxy]ethanone
CID 153092073
6-(3H-isoindol-5-yl)-N-[3-methoxy-4-(oxan-4-ylmethoxy)phenyl]imidazo[1,2-a]pyrazin-8-amine
CID 152848131
1-[4-[[6-(5H-cyclopenta[b]pyridin-3-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-3-methylazetidin-3-ol
CID 147069990
N-(3,4-dihydro-2H-chromen-6-yl)-6-(3H-inden-5-yl)imidazo[1,2-a]pyrazin-8-amine
CID 158225667
1-methyl-5-[8-(4-morpholin-4-ylanilino)imidazo[1,2-a]pyrazin-6-yl]-3H-indol-2-one
CID 149389474
N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]-4-pyridin-3-ylpyrimidin-2-amine
CID 175733112
(3S)-3-hydroxy-3-methyl-6-[8-(4-morpholin-4-ylanilino)imidazo[1,2-a]pyrazin-6-yl]-1H-inden-2-one
CID 158668845

Frequently Asked Questions

What is the IUPAC name of 6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine?
The IUPAC name of 6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine (CID 148617941) is 6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine.
What is the SMILES notation for 6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine?
The canonical SMILES for 6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine is CC(C)N1CCN(c2ccc(Nc3nc(-c4ccc5c(c4)CN=C5)cn4ccnc34)cn2)CC1.
What is the InChIKey of 6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine?
The InChIKey is NFRHGQMVKYJSPY-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H28N8/c1-18(2)32-9-11-33(12-10-32)24-6-5-22(16-29-24)30-25-26-28-7-8-34(26)17-23(31-25)19-3-4-20-14-27-15-21(20)13-19/h3-8,13-14,16-18H,9-12,15H2,1-2H3,(H,30,31).
What are the key properties of 6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine?
6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine has a molecular weight of 452.57 g/mol, XLogP of 4.00, 5 rotatable bonds, 1 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for 6-(3H-isoindol-5-yl)-N-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]imidazo[1,2-a]pyrazin-8-amine is sourced from PubChem (CID 148617941), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).