2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide

C133H104F22N20O12S2 — CID 158118343

About 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide

2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide (PubChem CID 158118343) has the molecular formula C133H104F22N20O12S2 and a molecular weight of 2656.51 g/mol. Its IUPAC name is 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide.

Molecular Properties

• Compound Name: 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide
• PubChem CID: 158118343
• Molecular Formula: C133H104F22N20O12S2
• Molecular Weight: 2656.51 g/mol
• Exact Mass: 2654.72
• IUPAC Name: 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide
• SMILES: CC(C)C(=O)Nc1cnc(-c2c(C(F)(F)F)oc3c2CCC3)cn1.Cc1ccccc1C(=O)Nc1cnc(-c2c(C(F)(F)F)oc3c2CCC3)cn1.Cc1ccccc1C(=O)Nc1cnc(-c2c(C)sc3c2CCC3)cn1.Cc1sc2c(c1-c1ccc(NC(=O)c3c(F)cccc3F)nc1)CCC2.O=C(Nc1cnc(-c2c(C(F)(F)F)oc3c2CCC3)cn1)c1c(F)cccc1F.O=C(Nc1cnc(-c2c(C(F)(F)F)oc3c2CCC3)cn1)c1c(F)cccc1F.O=C(Nc1cnc(-c2c(C(F)(F)F)oc3c2CCC3)cn1)c1ccccc1F
• InChI: InChI=1S/C20H16F3N3O2.C20H16F2N2OS.C20H19N3OS.2C19H12F5N3O2.C19H13F4N3O2.C16H16F3N3O2/c1-11-5-2-3-6-12(11)19(27)26-16-10-24-14(9-25-16)17-13-7-4-8-15(13)28-18(17)20(21,22)23;1-11-18(13-4-2-7-16(13)26-11)12-8-9-17(23-10-12)24-20(25)19-14(21)5-3-6-15(19)22;1-12-6-3-4-7-14(12)20(24)23-18-11-21-16(10-22-18)19-13(2)25-17-9-5-8-15(17)19;2*20-10-4-2-5-11(21)16(10)18(28)27-14-8-25-12(7-26-14)15-9-3-1-6-13(9)29-17(15)19(22,23)24;20-12-6-2-1-4-10(12)18(27)26-15-9-24-13(8-25-15)16-11-5-3-7-14(11)28-17(16)19(21,22)23;1-8(2)15(23)22-12-7-20-10(6-21-12)13-9-4-3-5-11(9)24-14(13)16(17,18)19/h2-3,5-6,9-10H,4,7-8H2,1H3,(H,25,26,27);3,5-6,8-10H,2,4,7H2,1H3,(H,23,24,25);3-4,6-7,10-11H,5,8-9H2,1-2H3,(H,22,23,24);2*2,4-5,7-8H,1,3,6H2,(H,26,27,28);1-2,4,6,8-9H,3,5,7H2,(H,25,26,27);6-8H,3-5H2,1-2H3,(H,21,22,23)
• InChIKey: FRHLDZONQXFLBB-UHFFFAOYSA-N
• XLogP: 32.53
• TPSA: 436.97 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 27
• Rotatable Bonds: 21
• Heavy Atoms: 189
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2656.51
LogP ≤ 5	32.53
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	27

Frequently Asked Questions

What is the IUPAC name of 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide?

The IUPAC name of 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide (CID 158118343) is 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide.

What is the SMILES notation for 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide?

The canonical SMILES for 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide is CC(C)C(=O)Nc1cnc(-c2c(C(F)(F)F)oc3c2CCC3)cn1.Cc1ccccc1C(=O)Nc1cnc(-c2c(C(F)(F)F)oc3c2CCC3)cn1.Cc1ccccc1C(=O)Nc1cnc(-c2c(C)sc3c2CCC3)cn1.Cc1sc2c(c1-c1ccc(NC(=O)c3c(F)cccc3F)nc1)CCC2.O=C(Nc1cnc(-c2c(C(F)(F)F)oc3c2CCC3)cn1)c1c(F)cccc1F.O=C(Nc1cnc(-c2c(C(F)(F)F)oc3c2CCC3)cn1)c1c(F)cccc1F.O=C(Nc1cnc(-c2c(C(F)(F)F)oc3c2CCC3)cn1)c1ccccc1F.

What is the InChIKey of 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide?

The InChIKey is FRHLDZONQXFLBB-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H16F3N3O2.C20H16F2N2OS.C20H19N3OS.2C19H12F5N3O2.C19H13F4N3O2.C16H16F3N3O2/c1-11-5-2-3-6-12(11)19(27)26-16-10-24-14(9-25-16)17-13-7-4-8-15(13)28-18(17)20(21,22)23;1-11-18(13-4-2-7-16(13)26-11)12-8-9-17(23-10-12)24-20(25)19-14(21)5-3-6-15(19)22;1-12-6-3-4-7-14(12)20(24)23-18-11-21-16(10-22-18)19-13(2)25-17-9-5-8-15(17)19;2*20-10-4-2-5-11(21)16(10)18(28)27-14-8-25-12(7-26-14)15-9-3-1-6-13(9)29-17(15)19(22,23)24;20-12-6-2-1-4-10(12)18(27)26-15-9-24-13(8-25-15)16-11-5-3-7-14(11)28-17(16)19(21,22)23;1-8(2)15(23)22-12-7-20-10(6-21-12)13-9-4-3-5-11(9)24-14(13)16(17,18)19/h2-3,5-6,9-10H,4,7-8H2,1H3,(H,25,26,27);3,5-6,8-10H,2,4,7H2,1H3,(H,23,24,25);3-4,6-7,10-11H,5,8-9H2,1-2H3,(H,22,23,24);2*2,4-5,7-8H,1,3,6H2,(H,26,27,28);1-2,4,6,8-9H,3,5,7H2,(H,25,26,27);6-8H,3-5H2,1-2H3,(H,21,22,23).

What are the key properties of 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide?

2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide has a molecular weight of 2656.51 g/mol, XLogP of 32.53, 21 rotatable bonds, 7 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;bis(2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide);2-fluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide is sourced from PubChem (CID 158118343), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).