1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione

C165H159F14N31O27S7 — CID 158630389

About 1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione

1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione (PubChem CID 158630389) has the molecular formula C165H159F14N31O27S7 and a molecular weight of 3498.72 g/mol. Its IUPAC name is 1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione.

Molecular Properties

• Compound Name: 1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione
• PubChem CID: 158630389
• Molecular Formula: C165H159F14N31O27S7
• Molecular Weight: 3498.72 g/mol
• Exact Mass: 3495.98
• IUPAC Name: 1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione
• SMILES: CC(=O)N1CCC2(CC1)Cn1cc(-c3nnc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c1C(=O)N2.CC(=O)N1CCC2(CC1)Cn1cc(-c3nnc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c1C(=O)N2C.CCC(c1nnc(-c2cn3c(c(O)c2=O)C(=O)N(CC)C2(CCOCC2)C3)s1)c1ccc(F)cc1F.CCCN1C(=O)c2c(O)c(=O)c(-c3nnc(Cc4ccc(F)cc4F)s3)cn2CC12CCOC2.CCN1C(=O)c2c(O)c(=O)c(-c3nnc(Cc4ccc(F)cc4F)s3)cn2CC12CCN(C(C)=O)CC2.CCN1C(=O)c2c(O)c(=O)c(-c3nnc(Cc4ccc(F)cc4F)s3)cn2CC12CCOCC2.O=C1NC2(CCCCC2)Cn2cc(-c3nnc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c21
• InChI: InChI=1S/C25H25F2N5O4S.C25H26F2N4O4S.C24H23F2N5O4S.C23H21F2N5O4S.2C23H22F2N4O4S.C22H20F2N4O3S/c1-3-32-24(36)20-22(35)21(34)17(12-31(20)13-25(32)6-8-30(9-7-25)14(2)33)23-29-28-19(37-23)10-15-4-5-16(26)11-18(15)27;1-3-15(16-6-5-14(26)11-18(16)27)22-28-29-23(36-22)17-12-30-13-25(7-9-35-10-8-25)31(4-2)24(34)19(30)21(33)20(17)32;1-13(32)30-7-5-24(6-8-30)12-31-11-16(20(33)21(34)19(31)23(35)29(24)2)22-28-27-18(36-22)9-14-3-4-15(25)10-17(14)26;1-12(31)29-6-4-23(5-7-29)11-30-10-15(19(32)20(33)18(30)21(34)26-23)22-28-27-17(35-22)8-13-2-3-14(24)9-16(13)25;1-2-29-22(32)18-20(31)19(30)15(11-28(18)12-23(29)5-7-33-8-6-23)21-27-26-17(34-21)9-13-3-4-14(24)10-16(13)25;1-2-6-29-22(32)18-20(31)19(30)15(10-28(18)11-23(29)5-7-33-12-23)21-27-26-17(34-21)8-13-3-4-14(24)9-16(13)25;23-13-5-4-12(15(24)9-13)8-16-26-27-21(32-16)14-10-28-11-22(6-2-1-3-7-22)25-20(31)17(28)19(30)18(14)29/h4-5,11-12,35H,3,6-10,13H2,1-2H3;5-6,11-12,15,33H,3-4,7-10,13H2,1-2H3;3-4,10-11,34H,5-9,12H2,1-2H3;2-3,9-10,33H,4-8,11H2,1H3,(H,26,34);3-4,10-11,31H,2,5-9,12H2,1H3;3-4,9-10,31H,2,5-8,11-12H2,1H3;4-5,9-10,30H,1-3,6-8,11H2,(H,25,31)
• InChIKey: HZCUAQILYUFQTK-UHFFFAOYSA-N
• XLogP: 20.51
• TPSA: 724.44 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 55
• Rotatable Bonds: 27
• Heavy Atoms: 244
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3498.72
LogP ≤ 5	20.51
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	55

Frequently Asked Questions

What is the IUPAC name of 1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione?

The IUPAC name of 1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione (CID 158630389) is 1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione.

What is the SMILES notation for 1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione?

The canonical SMILES for 1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione is CC(=O)N1CCC2(CC1)Cn1cc(-c3nnc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c1C(=O)N2.CC(=O)N1CCC2(CC1)Cn1cc(-c3nnc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c1C(=O)N2C.CCC(c1nnc(-c2cn3c(c(O)c2=O)C(=O)N(CC)C2(CCOCC2)C3)s1)c1ccc(F)cc1F.CCCN1C(=O)c2c(O)c(=O)c(-c3nnc(Cc4ccc(F)cc4F)s3)cn2CC12CCOC2.CCN1C(=O)c2c(O)c(=O)c(-c3nnc(Cc4ccc(F)cc4F)s3)cn2CC12CCN(C(C)=O)CC2.CCN1C(=O)c2c(O)c(=O)c(-c3nnc(Cc4ccc(F)cc4F)s3)cn2CC12CCOCC2.O=C1NC2(CCCCC2)Cn2cc(-c3nnc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c21.

What is the InChIKey of 1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione?

The InChIKey is HZCUAQILYUFQTK-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H25F2N5O4S.C25H26F2N4O4S.C24H23F2N5O4S.C23H21F2N5O4S.2C23H22F2N4O4S.C22H20F2N4O3S/c1-3-32-24(36)20-22(35)21(34)17(12-31(20)13-25(32)6-8-30(9-7-25)14(2)33)23-29-28-19(37-23)10-15-4-5-16(26)11-18(15)27;1-3-15(16-6-5-14(26)11-18(16)27)22-28-29-23(36-22)17-12-30-13-25(7-9-35-10-8-25)31(4-2)24(34)19(30)21(33)20(17)32;1-13(32)30-7-5-24(6-8-30)12-31-11-16(20(33)21(34)19(31)23(35)29(24)2)22-28-27-18(36-22)9-14-3-4-15(25)10-17(14)26;1-12(31)29-6-4-23(5-7-29)11-30-10-15(19(32)20(33)18(30)21(34)26-23)22-28-27-17(35-22)8-13-2-3-14(24)9-16(13)25;1-2-29-22(32)18-20(31)19(30)15(11-28(18)12-23(29)5-7-33-8-6-23)21-27-26-17(34-21)9-13-3-4-14(24)10-16(13)25;1-2-6-29-22(32)18-20(31)19(30)15(10-28(18)11-23(29)5-7-33-12-23)21-27-26-17(34-21)8-13-3-4-14(24)9-16(13)25;23-13-5-4-12(15(24)9-13)8-16-26-27-21(32-16)14-10-28-11-22(6-2-1-3-7-22)25-20(31)17(28)19(30)18(14)29/h4-5,11-12,35H,3,6-10,13H2,1-2H3;5-6,11-12,15,33H,3-4,7-10,13H2,1-2H3;3-4,10-11,34H,5-9,12H2,1-2H3;2-3,9-10,33H,4-8,11H2,1H3,(H,26,34);3-4,10-11,31H,2,5-9,12H2,1H3;3-4,9-10,31H,2,5-8,11-12H2,1H3;4-5,9-10,30H,1-3,6-8,11H2,(H,25,31).

What are the key properties of 1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione?

1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione has a molecular weight of 3498.72 g/mol, XLogP of 20.51, 27 rotatable bonds, 9 hydrogen bond donors, and 55 hydrogen bond acceptors.

Where does this data come from?

All data for 1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-methylspiro[4H-pyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;1'-acetyl-7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,4'-piperidine]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxy-2-propylspiro[4H-pyrido[1,2-a]pyrazine-3,3'-oxolane]-1,8-dione;7-[5-[(2,4-difluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-9-hydroxyspiro[2,4-dihydropyrido[1,2-a]pyrazine-3,1'-cyclohexane]-1,8-dione;7-[5-[1-(2,4-difluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]-2-ethyl-9-hydroxyspiro[4H-pyrido[1,2-a]pyrazine-3,4'-oxane]-1,8-dione is sourced from PubChem (CID 158630389), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).