6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide

C129H111F27N20O16S5 — CID 159105938

About 6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide

6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide (PubChem CID 159105938) has the molecular formula C129H111F27N20O16S5 and a molecular weight of 2870.71 g/mol. Its IUPAC name is 6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide.

Molecular Properties

• Compound Name: 6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide
• PubChem CID: 159105938
• Molecular Formula: C129H111F27N20O16S5
• Molecular Weight: 2870.71 g/mol
• Exact Mass: 2868.67
• IUPAC Name: 6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide
• SMILES: CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2-c1ccc(C(F)(F)F)cc1.CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2-c1cccc(C(F)(F)F)c1.CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2-c1cccc(C)c1.CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2-c1cccc(F)c1.CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2-c1cccc(OC)c1
• InChI: InChI=1S/2C26H21F7N4O3S.C26H24F4N4O4S.C26H24F4N4O3S.C25H21F5N4O3S/c1-3-14-10-21-18(11-19(14)27)22(24(34)38)23(37(21)16-6-4-15(5-7-16)26(31,32)33)20-9-8-17(12-35-20)41(39,40)36-13(2)25(28,29)30;1-3-14-9-21-18(11-19(14)27)22(24(34)38)23(37(21)16-6-4-5-15(10-16)26(31,32)33)20-8-7-17(12-35-20)41(39,40)36-13(2)25(28,29)30;1-4-15-10-22-19(12-20(15)27)23(25(31)35)24(34(22)16-6-5-7-17(11-16)38-3)21-9-8-18(13-32-21)39(36,37)33-14(2)26(28,29)30;1-4-16-11-22-19(12-20(16)27)23(25(31)35)24(34(22)17-7-5-6-14(2)10-17)21-9-8-18(13-32-21)38(36,37)33-15(3)26(28,29)30;1-3-14-9-21-18(11-19(14)27)22(24(31)35)23(34(21)16-6-4-5-15(26)10-16)20-8-7-17(12-32-20)38(36,37)33-13(2)25(28,29)30/h2*4-13,36H,3H2,1-2H3,(H2,34,38);5-14,33H,4H2,1-3H3,(H2,31,35);5-13,15,33H,4H2,1-3H3,(H2,31,35);4-13,33H,3H2,1-2H3,(H2,31,35)
• InChIKey: KDWQYTKECOGLLA-UHFFFAOYSA-N
• XLogP: 26.10
• TPSA: 544.63 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 26
• Rotatable Bonds: 36
• Heavy Atoms: 197
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2870.71
LogP ≤ 5	26.10
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	26

Frequently Asked Questions

What is the IUPAC name of 6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide?

The IUPAC name of 6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide (CID 159105938) is 6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide.

What is the SMILES notation for 6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide?

The canonical SMILES for 6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide is CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2-c1ccc(C(F)(F)F)cc1.CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2-c1cccc(C(F)(F)F)c1.CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2-c1cccc(C)c1.CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2-c1cccc(F)c1.CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2-c1cccc(OC)c1.

What is the InChIKey of 6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide?

The InChIKey is KDWQYTKECOGLLA-UHFFFAOYSA-N. The full InChI is InChI=1S/2C26H21F7N4O3S.C26H24F4N4O4S.C26H24F4N4O3S.C25H21F5N4O3S/c1-3-14-10-21-18(11-19(14)27)22(24(34)38)23(37(21)16-6-4-15(5-7-16)26(31,32)33)20-9-8-17(12-35-20)41(39,40)36-13(2)25(28,29)30;1-3-14-9-21-18(11-19(14)27)22(24(34)38)23(37(21)16-6-4-5-15(10-16)26(31,32)33)20-8-7-17(12-35-20)41(39,40)36-13(2)25(28,29)30;1-4-15-10-22-19(12-20(15)27)23(25(31)35)24(34(22)16-6-5-7-17(11-16)38-3)21-9-8-18(13-32-21)39(36,37)33-14(2)26(28,29)30;1-4-16-11-22-19(12-20(16)27)23(25(31)35)24(34(22)17-7-5-6-14(2)10-17)21-9-8-18(13-32-21)38(36,37)33-15(3)26(28,29)30;1-3-14-9-21-18(11-19(14)27)22(24(31)35)23(34(21)16-6-4-5-15(26)10-16)20-8-7-17(12-32-20)38(36,37)33-13(2)25(28,29)30/h2*4-13,36H,3H2,1-2H3,(H2,34,38);5-14,33H,4H2,1-3H3,(H2,31,35);5-13,15,33H,4H2,1-3H3,(H2,31,35);4-13,33H,3H2,1-2H3,(H2,31,35).

What are the key properties of 6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide?

6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide has a molecular weight of 2870.71 g/mol, XLogP of 26.10, 36 rotatable bonds, 10 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for 6-ethyl-5-fluoro-1-(3-fluorophenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methoxyphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-(3-methylphenyl)-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[3-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;6-ethyl-5-fluoro-1-[4-(trifluoromethyl)phenyl]-2-[5-(1,1,1-trifluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide is sourced from PubChem (CID 159105938), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).