6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide

C139H137F21N24O13S6 — CID 159106580

About 6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide

6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide (PubChem CID 159106580) has the molecular formula C139H137F21N24O13S6 and a molecular weight of 2943.14 g/mol. Its IUPAC name is 6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide.

Molecular Properties

• Compound Name: 6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
• PubChem CID: 159106580
• Molecular Formula: C139H137F21N24O13S6
• Molecular Weight: 2943.14 g/mol
• Exact Mass: 2940.88
• IUPAC Name: 6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
• SMILES: CC(C)(NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(OC(F)F)cc3n2C2CCC2)nc1)C(F)(F)F.CCc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(C)(C)C(F)(F)F)cn3)n(C3CCC3)c2c1.Cc1cc2c(C#N)c(-c3ccc(S(=O)(=O)NC(CF)CF)cn3)n(C3CCCC3)c2cc1F.Cc1cc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(C3CCCC3)c2cc1F.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(C)(C)C(F)(F)F)cn3)n(C3CCC3)c2c1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)NC(C)(C)C(F)(F)F)cn1)n2C1CCC1
• InChI: InChI=1S/C24H25F3N4O2S.C23H21F5N4O3S.C23H22F4N4O2S.3C23H23F3N4O2S/c1-4-15-8-10-18-19(13-28)22(31(21(18)12-15)16-6-5-7-16)20-11-9-17(14-29-20)34(32,33)30-23(2,3)24(25,26)27;1-22(2,23(26,27)28)31-36(33,34)15-7-9-18(30-12-15)20-17(11-29)16-8-6-14(35-21(24)25)10-19(16)32(20)13-4-3-5-13;1-13-9-17-18(11-28)22(31(15-5-3-4-6-15)21(17)10-19(13)24)20-8-7-16(12-29-20)34(32,33)30-14(2)23(25,26)27;1-14-7-10-20-17(11-14)18(12-27)21(30(20)15-5-4-6-15)19-9-8-16(13-28-19)33(31,32)29-22(2,3)23(24,25)26;1-14-7-9-17-18(12-27)21(30(20(17)11-14)15-5-4-6-15)19-10-8-16(13-28-19)33(31,32)29-22(2,3)23(24,25)26;1-14-8-18-19(12-27)23(30(16-4-2-3-5-16)22(18)9-20(14)26)21-7-6-17(13-28-21)33(31,32)29-15(10-24)11-25/h8-12,14,16,30H,4-7H2,1-3H3;6-10,12-13,21,31H,3-5H2,1-2H3;7-10,12,14-15,30H,3-6H2,1-2H3;2*7-11,13,15,29H,4-6H2,1-3H3;6-9,13,15-16,29H,2-5,10-11H2,1H3/t;;14-;;;/m..0.../s1
• InChIKey: KDYRAPMPNAKBNM-IPBPGIEUSA-N
• XLogP: 31.55
• TPSA: 535.91 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 31
• Rotatable Bonds: 35
• Heavy Atoms: 203
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2943.14
LogP ≤ 5	31.55
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	31

Frequently Asked Questions

What is the IUPAC name of 6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The IUPAC name of 6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide (CID 159106580) is 6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide.

What is the SMILES notation for 6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The canonical SMILES for 6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide is CC(C)(NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(OC(F)F)cc3n2C2CCC2)nc1)C(F)(F)F.CCc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(C)(C)C(F)(F)F)cn3)n(C3CCC3)c2c1.Cc1cc2c(C#N)c(-c3ccc(S(=O)(=O)NC(CF)CF)cn3)n(C3CCCC3)c2cc1F.Cc1cc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(C3CCCC3)c2cc1F.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(C)(C)C(F)(F)F)cn3)n(C3CCC3)c2c1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)NC(C)(C)C(F)(F)F)cn1)n2C1CCC1.

What is the InChIKey of 6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The InChIKey is KDYRAPMPNAKBNM-IPBPGIEUSA-N. The full InChI is InChI=1S/C24H25F3N4O2S.C23H21F5N4O3S.C23H22F4N4O2S.3C23H23F3N4O2S/c1-4-15-8-10-18-19(13-28)22(31(21(18)12-15)16-6-5-7-16)20-11-9-17(14-29-20)34(32,33)30-23(2,3)24(25,26)27;1-22(2,23(26,27)28)31-36(33,34)15-7-9-18(30-12-15)20-17(11-29)16-8-6-14(35-21(24)25)10-19(16)32(20)13-4-3-5-13;1-13-9-17-18(11-28)22(31(15-5-3-4-6-15)21(17)10-19(13)24)20-8-7-16(12-29-20)34(32,33)30-14(2)23(25,26)27;1-14-7-10-20-17(11-14)18(12-27)21(30(20)15-5-4-6-15)19-9-8-16(13-28-19)33(31,32)29-22(2,3)23(24,25)26;1-14-7-9-17-18(12-27)21(30(20(17)11-14)15-5-4-6-15)19-10-8-16(13-28-19)33(31,32)29-22(2,3)23(24,25)26;1-14-8-18-19(12-27)23(30(16-4-2-3-5-16)22(18)9-20(14)26)21-7-6-17(13-28-21)33(31,32)29-15(10-24)11-25/h8-12,14,16,30H,4-7H2,1-3H3;6-10,12-13,21,31H,3-5H2,1-2H3;7-10,12,14-15,30H,3-6H2,1-2H3;2*7-11,13,15,29H,4-6H2,1-3H3;6-9,13,15-16,29H,2-5,10-11H2,1H3/t;;14-;;;/m..0.../s1.

What are the key properties of 6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide has a molecular weight of 2943.14 g/mol, XLogP of 31.55, 35 rotatable bonds, 6 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for 6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoro-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide is sourced from PubChem (CID 159106580), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).