5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide

C123H117Cl3F5N41O11S — CID 159181303

About 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide

5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide (PubChem CID 159181303) has the molecular formula C123H117Cl3F5N41O11S and a molecular weight of 2578.98 g/mol. Its IUPAC name is 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide.

Molecular Properties

• Compound Name: 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide
• PubChem CID: 159181303
• Molecular Formula: C123H117Cl3F5N41O11S
• Molecular Weight: 2578.98 g/mol
• Exact Mass: 2575.86
• IUPAC Name: 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide
• SMILES: CC1OCCC1c1cc(Cl)cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(-c2ccncn2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(-c2cncs2)c1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(Cl)cc(-c3cccnc3)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(Cl)cc(-c3ncccn3)c2)cn1
• InChI: InChI=1S/C25H22ClFN8O2.C25H27ClFN7O3.C25H24FN9O2.C24H21ClFN9O2.C24H23FN8O2S/c26-18-10-17(16-2-1-5-28-13-16)11-20(12-18)31-19-3-4-22(29-14-19)24(36)33-34-25-30-15-21(27)23(32-25)35-6-8-37-9-7-35;1-15-20(4-7-37-15)16-10-17(26)12-19(11-16)30-18-2-3-22(28-13-18)24(35)32-33-25-29-14-21(27)23(31-25)34-5-8-36-9-6-34;1-16-10-17(21-4-5-27-15-30-21)12-19(11-16)31-18-2-3-22(28-13-18)24(36)33-34-25-29-14-20(26)23(32-25)35-6-8-37-9-7-35;25-16-10-15(21-27-4-1-5-28-21)11-18(12-16)31-17-2-3-20(29-13-17)23(36)33-34-24-30-14-19(26)22(32-24)35-6-8-37-9-7-35;1-15-8-16(21-13-26-14-36-21)10-18(9-15)29-17-2-3-20(27-11-17)23(34)31-32-24-28-12-19(25)22(30-24)33-4-6-35-7-5-33/h1-5,10-15,31H,6-9H2,(H,33,36)(H,30,32,34);2-3,10-15,20,30H,4-9H2,1H3,(H,32,35)(H,29,31,33);2-5,10-15,31H,6-9H2,1H3,(H,33,36)(H,29,32,34);1-5,10-14,31H,6-9H2,(H,33,36)(H,30,32,34);2-3,8-14,29H,4-7H2,1H3,(H,31,34)(H,28,30,32)
• InChIKey: KMXSPKGGNDMNIP-UHFFFAOYSA-N
• XLogP: 18.31
• TPSA: 608.07 Ų
• H-Bond Donors: 15
• H-Bond Acceptors: 48
• Rotatable Bonds: 35
• Heavy Atoms: 184
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2578.98
LogP ≤ 5	18.31
H-Bond Donors ≤ 5	15
H-Bond Acceptors ≤ 10	48

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide?

The IUPAC name of 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide (CID 159181303) is 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide.

What is the SMILES notation for 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide?

The canonical SMILES for 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide is CC1OCCC1c1cc(Cl)cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(-c2ccncn2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(-c2cncs2)c1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(Cl)cc(-c3cccnc3)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(Cl)cc(-c3ncccn3)c2)cn1.

What is the InChIKey of 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide?

The InChIKey is KMXSPKGGNDMNIP-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H22ClFN8O2.C25H27ClFN7O3.C25H24FN9O2.C24H21ClFN9O2.C24H23FN8O2S/c26-18-10-17(16-2-1-5-28-13-16)11-20(12-18)31-19-3-4-22(29-14-19)24(36)33-34-25-30-15-21(27)23(32-25)35-6-8-37-9-7-35;1-15-20(4-7-37-15)16-10-17(26)12-19(11-16)30-18-2-3-22(28-13-18)24(35)32-33-25-29-14-21(27)23(31-25)34-5-8-36-9-6-34;1-16-10-17(21-4-5-27-15-30-21)12-19(11-16)31-18-2-3-22(28-13-18)24(36)33-34-25-29-14-20(26)23(32-25)35-6-8-37-9-7-35;25-16-10-15(21-27-4-1-5-28-21)11-18(12-16)31-17-2-3-20(29-13-17)23(36)33-34-24-30-14-19(26)22(32-24)35-6-8-37-9-7-35;1-15-8-16(21-13-26-14-36-21)10-18(9-15)29-17-2-3-20(27-11-17)23(34)31-32-24-28-12-19(25)22(30-24)33-4-6-35-7-5-33/h1-5,10-15,31H,6-9H2,(H,33,36)(H,30,32,34);2-3,10-15,20,30H,4-9H2,1H3,(H,32,35)(H,29,31,33);2-5,10-15,31H,6-9H2,1H3,(H,33,36)(H,29,32,34);1-5,10-14,31H,6-9H2,(H,33,36)(H,30,32,34);2-3,8-14,29H,4-7H2,1H3,(H,31,34)(H,28,30,32).

What are the key properties of 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide?

5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide has a molecular weight of 2578.98 g/mol, XLogP of 18.31, 35 rotatable bonds, 15 hydrogen bond donors, and 48 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-methyl-5-pyrimidin-4-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide is sourced from PubChem (CID 159181303), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).