(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide

C124H148Cl2F2N24O11 — CID 159761719

About (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide

(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide (PubChem CID 159761719) has the molecular formula C124H148Cl2F2N24O11 and a molecular weight of 2259.61 g/mol. Its IUPAC name is (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide.

Molecular Properties

• Compound Name: (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide
• PubChem CID: 159761719
• Molecular Formula: C124H148Cl2F2N24O11
• Molecular Weight: 2259.61 g/mol
• Exact Mass: 2257.11
• IUPAC Name: (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide
• SMILES: CC(C)(C)n1c(NC(=O)C[C@](C)(O)c2ccccc2F)nc2ccc(Cl)nc21.Cc1ccc([C@@](C)(O)CC(=O)Nc2nc3cc(C)cnc3n2C2CCC2)cc1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3(C)CCC3)c2n1.Cc1cccc([C@@](C)(O)CC(=O)Nc2nc3cc(C)cnc3n2C2CCC2)c1.Cc1cccc([C@@](C)(O)CC(=O)Nc2nc3ccc(Cl)nc3n2C(C)(C)C)c1.Cc1cnc2c(c1)nc(NC(=O)C[C@](C)(O)c1ccccc1F)n2C1CCC1
• InChI: InChI=1S/2C22H26N4O2.C21H25ClN4O2.C21H23FN4O2.C20H22ClFN4O2.C18H26N4O/c1-14-6-4-7-16(10-14)22(3,28)12-19(27)25-21-24-18-11-15(2)13-23-20(18)26(21)17-8-5-9-17;1-14-7-9-16(10-8-14)22(3,28)12-19(27)25-21-24-18-11-15(2)13-23-20(18)26(21)17-5-4-6-17;1-13-7-6-8-14(11-13)21(5,28)12-17(27)25-19-23-15-9-10-16(22)24-18(15)26(19)20(2,3)4;1-13-10-17-19(23-12-13)26(14-6-5-7-14)20(24-17)25-18(27)11-21(2,28)15-8-3-4-9-16(15)22;1-19(2,3)26-17-14(9-10-15(21)24-17)23-18(26)25-16(27)11-20(4,28)12-7-5-6-8-13(12)22;1-12-7-8-13-15(19-12)22(18(5)9-6-10-18)16(20-13)21-14(23)11-17(2,3)4/h4,6-7,10-11,13,17,28H,5,8-9,12H2,1-3H3,(H,24,25,27);7-11,13,17,28H,4-6,12H2,1-3H3,(H,24,25,27);6-11,28H,12H2,1-5H3,(H,23,25,27);3-4,8-10,12,14,28H,5-7,11H2,1-2H3,(H,24,25,27);5-10,28H,11H2,1-4H3,(H,23,25,27);7-8H,6,9-11H2,1-5H3,(H,20,21,23)/t2*22-;2*21-;20-;/m00000./s1
• InChIKey: NEZALHDOLXVIHZ-PEYVNZQHSA-N
• XLogP: 24.47
• TPSA: 460.01 Ų
• H-Bond Donors: 11
• H-Bond Acceptors: 29
• Rotatable Bonds: 26
• Heavy Atoms: 163
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2259.61
LogP ≤ 5	24.47
H-Bond Donors ≤ 5	11
H-Bond Acceptors ≤ 10	29

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide?

The IUPAC name of (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide (CID 159761719) is (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide.

What is the SMILES notation for (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide?

The canonical SMILES for (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide is CC(C)(C)n1c(NC(=O)C[C@](C)(O)c2ccccc2F)nc2ccc(Cl)nc21.Cc1ccc([C@@](C)(O)CC(=O)Nc2nc3cc(C)cnc3n2C2CCC2)cc1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3(C)CCC3)c2n1.Cc1cccc([C@@](C)(O)CC(=O)Nc2nc3cc(C)cnc3n2C2CCC2)c1.Cc1cccc([C@@](C)(O)CC(=O)Nc2nc3ccc(Cl)nc3n2C(C)(C)C)c1.Cc1cnc2c(c1)nc(NC(=O)C[C@](C)(O)c1ccccc1F)n2C1CCC1.

What is the InChIKey of (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide?

The InChIKey is NEZALHDOLXVIHZ-PEYVNZQHSA-N. The full InChI is InChI=1S/2C22H26N4O2.C21H25ClN4O2.C21H23FN4O2.C20H22ClFN4O2.C18H26N4O/c1-14-6-4-7-16(10-14)22(3,28)12-19(27)25-21-24-18-11-15(2)13-23-20(18)26(21)17-8-5-9-17;1-14-7-9-16(10-8-14)22(3,28)12-19(27)25-21-24-18-11-15(2)13-23-20(18)26(21)17-5-4-6-17;1-13-7-6-8-14(11-13)21(5,28)12-17(27)25-19-23-15-9-10-16(22)24-18(15)26(19)20(2,3)4;1-13-10-17-19(23-12-13)26(14-6-5-7-14)20(24-17)25-18(27)11-21(2,28)15-8-3-4-9-16(15)22;1-19(2,3)26-17-14(9-10-15(21)24-17)23-18(26)25-16(27)11-20(4,28)12-7-5-6-8-13(12)22;1-12-7-8-13-15(19-12)22(18(5)9-6-10-18)16(20-13)21-14(23)11-17(2,3)4/h4,6-7,10-11,13,17,28H,5,8-9,12H2,1-3H3,(H,24,25,27);7-11,13,17,28H,4-6,12H2,1-3H3,(H,24,25,27);6-11,28H,12H2,1-5H3,(H,23,25,27);3-4,8-10,12,14,28H,5-7,11H2,1-2H3,(H,24,25,27);5-10,28H,11H2,1-4H3,(H,23,25,27);7-8H,6,9-11H2,1-5H3,(H,20,21,23)/t2*22-;2*21-;20-;/m00000./s1.

What are the key properties of (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide?

(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide has a molecular weight of 2259.61 g/mol, XLogP of 24.47, 26 rotatable bonds, 11 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide is sourced from PubChem (CID 159761719), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).