6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one

C93H80Cl4N24O4 — CID 159826375

IUPAC6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one
SMILESCn1cc(CNc2nc(-c3ccccc3)c(-c3cc(Cl)c4[nH]ncc4c3)[nH]c2=O)cn1.Cn1ccc(CNc2nc(-c3ccccc3)c(-c3cc(Cl)c4[nH]ncc4c3)[nH]c2=O)c1.O=c1[nH]c(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccccc2)nc1NCCC1CCCCC1.O=c1[nH]c(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccccc2)nc1NCc1cccnc1
InChIInChI=1S/C25H26ClN5O.C23H19ClN6O.C23H17ClN6O.C22H18ClN7O/c26-20-14-18(13-19-15-28-31-21(19)20)23-22(17-9-5-2-6-10-17)29-24(25(32)30-23)27-12-11-16-7-3-1-4-8-16;1-30-8-7-14(13-30)11-25-22-23(31)28-21(20(27-22)15-5-3-2-4-6-15)16-9-17-12-26-29-19(17)18(24)10-16;24-18-10-16(9-17-13-27-30-19(17)18)21-20(15-6-2-1-3-7-15)28-22(23(31)29-21)26-12-14-5-4-8-25-11-14;1-30-12-13(10-26-30)9-24-21-22(31)28-20(19(27-21)14-5-3-2-4-6-14)15-7-16-11-25-29-18(16)17(23)8-15/h2,5-6,9-10,13-16H,1,3-4,7-8,11-12H2,(H,27,29)(H,28,31)(H,30,32);2-10,12-13H,11H2,1H3,(H,25,27)(H,26,29)(H,28,31);1-11,13H,12H2,(H,26,28)(H,27,30)(H,29,31);2-8,10-12H,9H2,1H3,(H,24,27)(H,25,29)(H,28,31)
InChIKeyNMWSKJAGSAKUCF-UHFFFAOYSA-N
MW1739.64 g/mol
LogP19.22
Rot. Bonds21

About 6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one

6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one (PubChem CID 159826375) has the molecular formula C93H80Cl4N24O4 and a molecular weight of 1739.64 g/mol. Its IUPAC name is 6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one.

Molecular Properties

Compound Name6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one
PubChem CID159826375
Molecular FormulaC93H80Cl4N24O4
Molecular Weight1739.64 g/mol
Exact Mass1736.55
IUPAC Name6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one
SMILESCn1cc(CNc2nc(-c3ccccc3)c(-c3cc(Cl)c4[nH]ncc4c3)[nH]c2=O)cn1.Cn1ccc(CNc2nc(-c3ccccc3)c(-c3cc(Cl)c4[nH]ncc4c3)[nH]c2=O)c1.O=c1[nH]c(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccccc2)nc1NCCC1CCCCC1.O=c1[nH]c(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccccc2)nc1NCc1cccnc1
InChIInChI=1S/C25H26ClN5O.C23H19ClN6O.C23H17ClN6O.C22H18ClN7O/c26-20-14-18(13-19-15-28-31-21(19)20)23-22(17-9-5-2-6-10-17)29-24(25(32)30-23)27-12-11-16-7-3-1-4-8-16;1-30-8-7-14(13-30)11-25-22-23(31)28-21(20(27-22)15-5-3-2-4-6-15)16-9-17-12-26-29-19(17)18(24)10-16;24-18-10-16(9-17-13-27-30-19(17)18)21-20(15-6-2-1-3-7-15)28-22(23(31)29-21)26-12-14-5-4-8-25-11-14;1-30-12-13(10-26-30)9-24-21-22(31)28-20(19(27-21)14-5-3-2-4-6-14)15-7-16-11-25-29-18(16)17(23)8-15/h2,5-6,9-10,13-16H,1,3-4,7-8,11-12H2,(H,27,29)(H,28,31)(H,30,32);2-10,12-13H,11H2,1H3,(H,25,27)(H,26,29)(H,28,31);1-11,13H,12H2,(H,26,28)(H,27,30)(H,29,31);2-8,10-12H,9H2,1H3,(H,24,27)(H,25,29)(H,28,31)
InChIKeyNMWSKJAGSAKUCF-UHFFFAOYSA-N
XLogP19.22
TPSA381.48 Ų
H-Bond Donors12
H-Bond Acceptors20
Rotatable Bonds21
Heavy Atoms125
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001739.64
LogP ≤ 519.22
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1020

Analyze 6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one with MolForge

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Launch Full Analysis

Related Compounds

6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one
CID 137431197
6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one
CID 137431201
6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(2-pyridin-4-ylethylamino)-1H-pyrazin-2-one
CID 137431659
6-(7-chloro-1H-indazol-5-yl)-3-[2-(1-methylpyrrol-3-yl)ethylamino]-5-phenyl-1H-pyrazin-2-one
CID 137431666
3-(but-2-ynylamino)-6-(7-chloro-1H-indazol-5-yl)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpiperidin-4-yl)amino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrolidin-3-yl)amino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(prop-2-enylamino)-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(prop-2-ynylamino)-1H-pyrazin-2-one
CID 157214438
1-[3-amino-6-(7-chloro-1H-indazol-5-yl)-5-phenylpyrazin-2-yl]-3-[2-(diethylamino)ethyl]urea;1-[3-amino-6-(7-chloro-1H-indazol-5-yl)-5-phenylpyrazin-2-yl]-3-(4-methylphenyl)urea;1-[3-amino-6-(7-chloro-1H-indazol-5-yl)-5-phenylpyrazin-2-yl]-3-(6-methyl-3-pyridinyl)urea;N-[3-amino-6-(7-chloro-1H-indazol-5-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide
CID 157312784
N-[6-(7-chloro-1H-indazol-5-yl)-2-oxo-5-phenyl-1H-pyrazin-3-yl]cyclopropanesulfonamide;N-[6-(7-chloro-1H-indazol-5-yl)-2-oxo-5-phenyl-1H-pyrazin-3-yl]ethanesulfonamide;N-[6-(7-chloro-1H-indazol-5-yl)-2-oxo-5-phenyl-1H-pyrazin-3-yl]methanesulfonamide;1-[6-(7-chloro-1H-indazol-5-yl)-2-oxo-5-phenyl-1H-pyrazin-3-yl]-3-[(2-methylpyrimidin-5-yl)methyl]urea;1-[6-(7-chloro-1H-indazol-5-yl)-2-oxo-5-phenyl-1H-pyrazin-3-yl]-3-(pyridin-3-ylmethyl)urea
CID 157453899
2-[2-(benzylamino)ethylamino]-2-(3-chlorophenyl)-N-(1H-indazol-5-yl)acetamide;2-(3-chlorophenyl)-2-[2-(ethylamino)ethylamino]-N-(1H-indazol-5-yl)acetamide;2-(3-chlorophenyl)-N-(1H-indazol-5-yl)-2-[3-(methylamino)propylamino]acetamide;2-(3-chlorophenyl)-N-(1H-indazol-5-yl)-2-(2-pyridin-2-ylethylamino)acetamide;2-(3-chlorophenyl)-N-(1H-indazol-5-yl)-2-(pyridin-2-ylmethylamino)acetamide
CID 158172515
5-(7-chloro-1H-indazol-5-yl)-3-N,6-diphenylpyrazine-2,3-diamine;5-(7-chloro-1H-indazol-5-yl)-3-N-(1-methylazetidin-3-yl)-6-phenylpyrazine-2,3-diamine;5-(7-chloro-1H-indazol-5-yl)-3-N-(1-methylpiperidin-4-yl)-6-phenylpyrazine-2,3-diamine;5-(7-chloro-1H-indazol-5-yl)-3-N-(1-methylpyrrolidin-3-yl)-6-phenylpyrazine-2,3-diamine;5-(7-chloro-1H-indazol-5-yl)-3-N-(1-methylpyrrol-3-yl)-6-phenylpyrazine-2,3-diamine;5-(7-chloro-1H-indazol-5-yl)-6-phenyl-3-N-pyridin-3-ylpyrazine-2,3-diamine
CID 158532425
bis(3-(benzylamino)-6-(7-chloro-1H-indazol-5-yl)-5-phenylpyrazine-2-carbonitrile);6-(7-chloro-1H-indazol-5-yl)-3-[2-(1-methylpyrrol-3-yl)ethylamino]-5-phenylpyrazine-2-carbonitrile;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(2-phenylethylamino)pyrazine-2-carbonitrile
CID 158901549
3-(tert-butylamino)-6-(8-chloroquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-[[6-(7-chloro-1H-indazol-5-yl)-2-oxo-5-phenyl-1H-pyrazin-3-yl]amino]-N-(6-cyano-3-pyridinyl)propanamide;3-[[6-(7-chloro-1H-indazol-5-yl)-2-oxo-5-phenyl-1H-pyrazin-3-yl]amino]-N-cyclopropylpropanamide;6-(8-chloroquinolin-6-yl)-3-(ethylamino)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;6-(8-chloroquinolin-6-yl)-5-(1-methylpyrazol-3-yl)-3-(propan-2-ylamino)pyrazine-2-carbonitrile
CID 159257704
1-benzyl-3-[6-(7-chloro-1H-indazol-5-yl)-2-oxo-5-phenyl-1H-pyrazin-3-yl]urea;1-[6-(7-chloro-1H-indazol-5-yl)-2-oxo-5-phenyl-1H-pyrazin-3-yl]-3-cyclobutylurea;1-[6-(7-chloro-1H-indazol-5-yl)-2-oxo-5-phenyl-1H-pyrazin-3-yl]-3-(cyclopentylmethyl)urea;1-[6-(7-chloro-1H-indazol-5-yl)-2-oxo-5-phenyl-1H-pyrazin-3-yl]-3-[(1-methylazetidin-3-yl)methyl]urea;1-[6-(7-chloro-1H-indazol-5-yl)-2-oxo-5-phenyl-1H-pyrazin-3-yl]-3-(1-methylpiperidin-4-yl)urea
CID 159291829

Frequently Asked Questions

What is the IUPAC name of 6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one?
The IUPAC name of 6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one (CID 159826375) is 6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one.
What is the SMILES notation for 6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one?
The canonical SMILES for 6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one is Cn1cc(CNc2nc(-c3ccccc3)c(-c3cc(Cl)c4[nH]ncc4c3)[nH]c2=O)cn1.Cn1ccc(CNc2nc(-c3ccccc3)c(-c3cc(Cl)c4[nH]ncc4c3)[nH]c2=O)c1.O=c1[nH]c(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccccc2)nc1NCCC1CCCCC1.O=c1[nH]c(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccccc2)nc1NCc1cccnc1.
What is the InChIKey of 6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one?
The InChIKey is NMWSKJAGSAKUCF-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H26ClN5O.C23H19ClN6O.C23H17ClN6O.C22H18ClN7O/c26-20-14-18(13-19-15-28-31-21(19)20)23-22(17-9-5-2-6-10-17)29-24(25(32)30-23)27-12-11-16-7-3-1-4-8-16;1-30-8-7-14(13-30)11-25-22-23(31)28-21(20(27-22)15-5-3-2-4-6-15)16-9-17-12-26-29-19(17)18(24)10-16;24-18-10-16(9-17-13-27-30-19(17)18)21-20(15-6-2-1-3-7-15)28-22(23(31)29-21)26-12-14-5-4-8-25-11-14;1-30-12-13(10-26-30)9-24-21-22(31)28-20(19(27-21)14-5-3-2-4-6-14)15-7-16-11-25-29-18(16)17(23)8-15/h2,5-6,9-10,13-16H,1,3-4,7-8,11-12H2,(H,27,29)(H,28,31)(H,30,32);2-10,12-13H,11H2,1H3,(H,25,27)(H,26,29)(H,28,31);1-11,13H,12H2,(H,26,28)(H,27,30)(H,29,31);2-8,10-12H,9H2,1H3,(H,24,27)(H,25,29)(H,28,31).
What are the key properties of 6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one?
6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one has a molecular weight of 1739.64 g/mol, XLogP of 19.22, 21 rotatable bonds, 12 hydrogen bond donors, and 20 hydrogen bond acceptors.
Where does this data come from?
All data for 6-(7-chloro-1H-indazol-5-yl)-3-(2-cyclohexylethylamino)-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrazol-4-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpyrrol-3-yl)methylamino]-5-phenyl-1H-pyrazin-2-one;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(pyridin-3-ylmethylamino)-1H-pyrazin-2-one is sourced from PubChem (CID 159826375), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).