2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine

C124H98F9N23S6 — CID 160524471

About 2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine

2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine (PubChem CID 160524471) has the molecular formula C124H98F9N23S6 and a molecular weight of 2273.69 g/mol. Its IUPAC name is 2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine.

Molecular Properties

• Compound Name: 2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine
• PubChem CID: 160524471
• Molecular Formula: C124H98F9N23S6
• Molecular Weight: 2273.69 g/mol
• Exact Mass: 2271.66
• IUPAC Name: 2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine
• SMILES: CNc1ccc(-c2cc3ccc(-c4ccc(F)nc4)nc3s2)cc1F.CNc1ccc(-c2cc3ccc(-c4ccc(N5CC[C@@H](F)C5)nc4)nc3s2)cc1F.CNc1ccc(-c2cc3ccc(-c4ccc(N5CC[C@H](F)C5)nc4)nc3s2)cc1F.Cc1ccc(-c2cc3ccc(-c4ccc(F)nc4)nc3s2)cn1.F[C@H]1CCN(c2ccc(-c3ccc4cc(-c5cccnc5)sc4n3)cn2)C1.Fc1nc(N2CCCC2)ccc1-c1ccc2cc(-c3cncnc3)sc2n1
• InChI: InChI=1S/2C23H20F2N4S.C21H17FN4S.C20H16FN5S.C19H13F2N3S.C18H12FN3S/c2*1-26-20-6-2-14(10-18(20)25)21-11-15-3-5-19(28-23(15)30-21)16-4-7-22(27-12-16)29-9-8-17(24)13-29;22-17-7-9-26(13-17)20-6-4-15(12-24-20)18-5-3-14-10-19(27-21(14)25-18)16-2-1-8-23-11-16;21-19-15(4-6-18(25-19)26-7-1-2-8-26)16-5-3-13-9-17(27-20(13)24-16)14-10-22-12-23-11-14;1-22-16-6-2-11(8-14(16)20)17-9-12-3-5-15(24-19(12)25-17)13-4-7-18(21)23-10-13;1-11-2-3-14(10-20-11)16-8-12-4-6-15(22-18(12)23-16)13-5-7-17(19)21-9-13/h2*2-7,10-12,17,26H,8-9,13H2,1H3;1-6,8,10-12,17H,7,9,13H2;3-6,9-12H,1-2,7-8H2;2-10,22H,1H3;2-10H,1H3/t3*17-;;;/m100.../s1
• InChIKey: QUSAOQPBVXXYTO-FUFWBEJTSA-N
• XLogP: 31.24
• TPSA: 255.29 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 29
• Rotatable Bonds: 19
• Heavy Atoms: 162
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2273.69
LogP ≤ 5	31.24
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	29

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine?

The IUPAC name of 2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine (CID 160524471) is 2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine.

What is the SMILES notation for 2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine?

The canonical SMILES for 2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine is CNc1ccc(-c2cc3ccc(-c4ccc(F)nc4)nc3s2)cc1F.CNc1ccc(-c2cc3ccc(-c4ccc(N5CC[C@@H](F)C5)nc4)nc3s2)cc1F.CNc1ccc(-c2cc3ccc(-c4ccc(N5CC[C@H](F)C5)nc4)nc3s2)cc1F.Cc1ccc(-c2cc3ccc(-c4ccc(F)nc4)nc3s2)cn1.F[C@H]1CCN(c2ccc(-c3ccc4cc(-c5cccnc5)sc4n3)cn2)C1.Fc1nc(N2CCCC2)ccc1-c1ccc2cc(-c3cncnc3)sc2n1.

What is the InChIKey of 2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine?

The InChIKey is QUSAOQPBVXXYTO-FUFWBEJTSA-N. The full InChI is InChI=1S/2C23H20F2N4S.C21H17FN4S.C20H16FN5S.C19H13F2N3S.C18H12FN3S/c2*1-26-20-6-2-14(10-18(20)25)21-11-15-3-5-19(28-23(15)30-21)16-4-7-22(27-12-16)29-9-8-17(24)13-29;22-17-7-9-26(13-17)20-6-4-15(12-24-20)18-5-3-14-10-19(27-21(14)25-18)16-2-1-8-23-11-16;21-19-15(4-6-18(25-19)26-7-1-2-8-26)16-5-3-13-9-17(27-20(13)24-16)14-10-22-12-23-11-14;1-22-16-6-2-11(8-14(16)20)17-9-12-3-5-15(24-19(12)25-17)13-4-7-18(21)23-10-13;1-11-2-3-14(10-20-11)16-8-12-4-6-15(22-18(12)23-16)13-5-7-17(19)21-9-13/h2*2-7,10-12,17,26H,8-9,13H2,1H3;1-6,8,10-12,17H,7,9,13H2;3-6,9-12H,1-2,7-8H2;2-10,22H,1H3;2-10H,1H3/t3*17-;;;/m100.../s1.

What are the key properties of 2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine?

2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine has a molecular weight of 2273.69 g/mol, XLogP of 31.24, 19 rotatable bonds, 3 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for 2-fluoro-4-[6-(6-fluoro-3-pyridinyl)thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;2-fluoro-4-[6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]thieno[2,3-b]pyridin-2-yl]-N-methylaniline;6-(6-fluoro-3-pyridinyl)-2-(6-methyl-3-pyridinyl)thieno[2,3-b]pyridine;6-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-2-pyridin-3-ylthieno[2,3-b]pyridine;6-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-2-pyrimidin-5-ylthieno[2,3-b]pyridine is sourced from PubChem (CID 160524471), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).