2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine

C114H100Cl2F6N24O2 — CID 161037393

About 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine

2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine (PubChem CID 161037393) has the molecular formula C114H100Cl2F6N24O2 and a molecular weight of 2023.11 g/mol. Its IUPAC name is 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine.

Molecular Properties

• Compound Name: 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine
• PubChem CID: 161037393
• Molecular Formula: C114H100Cl2F6N24O2
• Molecular Weight: 2023.11 g/mol
• Exact Mass: 2020.77
• IUPAC Name: 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine
• SMILES: CCN1CCC(n2cc(-c3cncc(-c4cc(-c5cc(Cl)ccc5F)nc5ncccc45)c3)cn2)CC1.Fc1ccc(F)c(-c2cc(-c3cncc(-c4cnn(C5CCNCC5)c4)c3)c3cccnc3n2)c1.Fc1ccc(F)c(-c2cc(-c3cncc(-c4cnn(CCCN5CCOCC5)c4)c3)c3cccnc3n2)c1.OCCN1CCC(n2cc(-c3cncc(-c4cc(-c5cc(Cl)ccc5F)nc5ncccc45)c3)cn2)CC1
• InChI: InChI=1S/C29H26ClFN6O.C29H26ClFN6.C29H26F2N6O.C27H22F2N6/c30-22-3-4-27(31)26(13-22)28-14-25(24-2-1-7-33-29(24)35-28)20-12-19(15-32-16-20)21-17-34-37(18-21)23-5-8-36(9-6-23)10-11-38;1-2-36-10-7-23(8-11-36)37-18-21(17-34-37)19-12-20(16-32-15-19)25-14-28(26-13-22(30)5-6-27(26)31)35-29-24(25)4-3-9-33-29;30-23-4-5-27(31)26(14-23)28-15-25(24-3-1-6-33-29(24)35-28)21-13-20(16-32-17-21)22-18-34-37(19-22)8-2-7-36-9-11-38-12-10-36;28-20-3-4-25(29)24(11-20)26-12-23(22-2-1-7-32-27(22)34-26)18-10-17(13-31-14-18)19-15-33-35(16-19)21-5-8-30-9-6-21/h1-4,7,12-18,23,38H,5-6,8-11H2;3-6,9,12-18,23H,2,7-8,10-11H2,1H3;1,3-6,13-19H,2,7-12H2;1-4,7,10-16,21,30H,5-6,8-9H2
• InChIKey: UAKWEWRYIBKIGM-UHFFFAOYSA-N
• XLogP: 22.96
• TPSA: 277.17 Ų
• H-Bond Donors: 2
• H-Bond Acceptors: 26
• Rotatable Bonds: 22
• Heavy Atoms: 148
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2023.11
LogP ≤ 5	22.96
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	26

Frequently Asked Questions

What is the IUPAC name of 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine?

The IUPAC name of 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine (CID 161037393) is 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine.

What is the SMILES notation for 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine?

The canonical SMILES for 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine is CCN1CCC(n2cc(-c3cncc(-c4cc(-c5cc(Cl)ccc5F)nc5ncccc45)c3)cn2)CC1.Fc1ccc(F)c(-c2cc(-c3cncc(-c4cnn(C5CCNCC5)c4)c3)c3cccnc3n2)c1.Fc1ccc(F)c(-c2cc(-c3cncc(-c4cnn(CCCN5CCOCC5)c4)c3)c3cccnc3n2)c1.OCCN1CCC(n2cc(-c3cncc(-c4cc(-c5cc(Cl)ccc5F)nc5ncccc45)c3)cn2)CC1.

What is the InChIKey of 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine?

The InChIKey is UAKWEWRYIBKIGM-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H26ClFN6O.C29H26ClFN6.C29H26F2N6O.C27H22F2N6/c30-22-3-4-27(31)26(13-22)28-14-25(24-2-1-7-33-29(24)35-28)20-12-19(15-32-16-20)21-17-34-37(18-21)23-5-8-36(9-6-23)10-11-38;1-2-36-10-7-23(8-11-36)37-18-21(17-34-37)19-12-20(16-32-15-19)25-14-28(26-13-22(30)5-6-27(26)31)35-29-24(25)4-3-9-33-29;30-23-4-5-27(31)26(14-23)28-15-25(24-3-1-6-33-29(24)35-28)21-13-20(16-32-17-21)22-18-34-37(19-22)8-2-7-36-9-11-38-12-10-36;28-20-3-4-25(29)24(11-20)26-12-23(22-2-1-7-32-27(22)34-26)18-10-17(13-31-14-18)19-15-33-35(16-19)21-5-8-30-9-6-21/h1-4,7,12-18,23,38H,5-6,8-11H2;3-6,9,12-18,23H,2,7-8,10-11H2,1H3;1,3-6,13-19H,2,7-12H2;1-4,7,10-16,21,30H,5-6,8-9H2.

What are the key properties of 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine?

2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine has a molecular weight of 2023.11 g/mol, XLogP of 22.96, 22 rotatable bonds, 2 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-[4-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]piperidin-1-yl]ethanol;4-[3-[4-[5-[2-(2,5-difluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]propyl]morpholine;2-(2,5-difluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine is sourced from PubChem (CID 161037393), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).