4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one

C19H14N2O3S — CID 162629528

IUPAC4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one
SMILESCOc1ncccc1-c1ccc2[nH]c(=O)c(-c3cccs3)c(O)c2c1
InChIInChI=1S/C19H14N2O3S/c1-24-19-12(4-2-8-20-19)11-6-7-14-13(10-11)17(22)16(18(23)21-14)15-5-3-9-25-15/h2-10H,1H3,(H2,21,22,23)
InChIKeyQKHRGCHHESZVLB-UHFFFAOYSA-N
MW350.40 g/mol
LogP4.03
Rot. Bonds3

About 4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one

4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one (PubChem CID 162629528) has the molecular formula C19H14N2O3S and a molecular weight of 350.40 g/mol. Its IUPAC name is 4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one.

Molecular Properties

Compound Name4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one
PubChem CID162629528
Molecular FormulaC19H14N2O3S
Molecular Weight350.40 g/mol
Exact Mass350.07
IUPAC Name4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one
SMILESCOc1ncccc1-c1ccc2[nH]c(=O)c(-c3cccs3)c(O)c2c1
InChIInChI=1S/C19H14N2O3S/c1-24-19-12(4-2-8-20-19)11-6-7-14-13(10-11)17(22)16(18(23)21-14)15-5-3-9-25-15/h2-10H,1H3,(H2,21,22,23)
InChIKeyQKHRGCHHESZVLB-UHFFFAOYSA-N
XLogP4.03
TPSA75.21 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds3
Heavy Atoms25
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500350.40
LogP ≤ 54.03
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

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Related Compounds

4-hydroxy-6-(1H-pyrazol-5-yl)-3-thiophen-2-yl-1H-quinolin-2-one
CID 162632669
5-(2-methoxy-3-pyridinyl)-1H-indazol-3-amine
CID 68739130
4-hydroxy-6-[3-(morpholine-4-carbonyl)phenyl]-3-thiophen-2-yl-1H-quinolin-2-one
CID 162634116
7-chloro-4-hydroxy-3-thiophen-2-yl-1H-1,5-naphthyridin-2-one
CID 54730141
4-[2-oxo-4-(pyridin-2-ylmethoxy)-3-thiophen-2-yl-1H-quinolin-6-yl]benzonitrile
CID 50917960
4-[(3-chlorophenyl)methylamino]-6-(2-methoxy-3-pyridinyl)-1H-quinolin-2-one
CID 121342339
6-(2-methoxy-3-pyridinyl)-1H-benzimidazole
CID 50963824
6-(2-methoxy-3-pyridinyl)spiro[1H-indole-3,1'-cyclopropane]-2-one
CID 138051431
4-hydroxy-7-methoxy-3-(2-methoxyphenyl)-1H-quinolin-2-one
CID 54691271
3-(5-ethyl-1,3,4-oxadiazol-2-yl)-5-thiophen-2-yl-1H-1,6-naphthyridin-2-one
CID 135574483
tert-butyl 3-(2-methoxy-3-pyridinyl)-5-methyl-1H-indole-2-carboxylate
CID 58132246
5-methoxy-2-methyl-3-thiophen-2-yl-1H-indole
CID 53235789

Frequently Asked Questions

What is the IUPAC name of 4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one?
The IUPAC name of 4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one (CID 162629528) is 4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one.
What is the SMILES notation for 4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one?
The canonical SMILES for 4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one is COc1ncccc1-c1ccc2[nH]c(=O)c(-c3cccs3)c(O)c2c1.
What is the InChIKey of 4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one?
The InChIKey is QKHRGCHHESZVLB-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H14N2O3S/c1-24-19-12(4-2-8-20-19)11-6-7-14-13(10-11)17(22)16(18(23)21-14)15-5-3-9-25-15/h2-10H,1H3,(H2,21,22,23).
What are the key properties of 4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one?
4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one has a molecular weight of 350.40 g/mol, XLogP of 4.03, 3 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 4-hydroxy-6-(2-methoxy-3-pyridinyl)-3-thiophen-2-yl-1H-quinolin-2-one is sourced from PubChem (CID 162629528), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).