5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

C117H121ClF12N32O9 — CID 163413630

IUPAC5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCCc1cc(-c2ccccn2)nc2c(C(=O)NC(C)C3CC4(CCC4)C3)cnn12.COc1cccc(-c2cc(C)n3ncc(C(=O)NC(C4CC4)C(F)(F)F)c3n2)n1.Cc1cc(-c2cccc3ncoc23)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2ccccn2)nc2c(C(=O)NC(C)C(C)C3CC3)cnn12.Cc1cc(-n2ccc(Cl)n2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12.Cc1cc(N2CCN(C(C)C)C2=O)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12
InChIInChI=1S/C23H27N5O.C20H16F3N5O2.C20H23N5O.C19H23F3N6O2.C19H18F3N5O2.C16H14ClF3N6O/c1-3-17-11-20(19-7-4-5-10-24-19)27-21-18(14-25-28(17)21)22(29)26-15(2)16-12-23(13-16)8-6-9-23;1-10-7-15(12-3-2-4-14-16(12)30-9-24-14)26-18-13(8-25-28(10)18)19(29)27-17(11-5-6-11)20(21,22)23;1-12-10-18(17-6-4-5-9-21-17)24-19-16(11-22-25(12)19)20(26)23-14(3)13(2)15-7-8-15;1-10(2)26-6-7-27(18(26)30)14-8-11(3)28-16(24-14)13(9-23-28)17(29)25-15(12-4-5-12)19(20,21)22;1-10-8-14(13-4-3-5-15(24-13)29-2)25-17-12(9-23-27(10)17)18(28)26-16(11-6-7-11)19(20,21)22;1-8-6-12(25-5-4-11(17)24-25)22-14-10(7-21-26(8)14)15(27)23-13(9-2-3-9)16(18,19)20/h4-5,7,10-11,14-16H,3,6,8-9,12-13H2,1-2H3,(H,26,29);2-4,7-9,11,17H,5-6H2,1H3,(H,27,29);4-6,9-11,13-15H,7-8H2,1-3H3,(H,23,26);8-10,12,15H,4-7H2,1-3H3,(H,25,29);3-5,8-9,11,16H,6-7H2,1-2H3,(H,26,28);4-7,9,13H,2-3H2,1H3,(H,23,27)
InChIKeyACOLEDGYFACYBX-UHFFFAOYSA-N
MW2382.90 g/mol
LogP20.12
Rot. Bonds28

About 5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 163413630) has the molecular formula C117H121ClF12N32O9 and a molecular weight of 2382.90 g/mol. Its IUPAC name is 5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

Compound Name5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
PubChem CID163413630
Molecular FormulaC117H121ClF12N32O9
Molecular Weight2382.90 g/mol
Exact Mass2380.95
IUPAC Name5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCCc1cc(-c2ccccn2)nc2c(C(=O)NC(C)C3CC4(CCC4)C3)cnn12.COc1cccc(-c2cc(C)n3ncc(C(=O)NC(C4CC4)C(F)(F)F)c3n2)n1.Cc1cc(-c2cccc3ncoc23)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2ccccn2)nc2c(C(=O)NC(C)C(C)C3CC3)cnn12.Cc1cc(-n2ccc(Cl)n2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12.Cc1cc(N2CCN(C(C)C)C2=O)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12
InChIInChI=1S/C23H27N5O.C20H16F3N5O2.C20H23N5O.C19H23F3N6O2.C19H18F3N5O2.C16H14ClF3N6O/c1-3-17-11-20(19-7-4-5-10-24-19)27-21-18(14-25-28(17)21)22(29)26-15(2)16-12-23(13-16)8-6-9-23;1-10-7-15(12-3-2-4-14-16(12)30-9-24-14)26-18-13(8-25-28(10)18)19(29)27-17(11-5-6-11)20(21,22)23;1-12-10-18(17-6-4-5-9-21-17)24-19-16(11-22-25(12)19)20(26)23-14(3)13(2)15-7-8-15;1-10(2)26-6-7-27(18(26)30)14-8-11(3)28-16(24-14)13(9-23-28)17(29)25-15(12-4-5-12)19(20,21)22;1-10-8-14(13-4-3-5-15(24-13)29-2)25-17-12(9-23-27(10)17)18(28)26-16(11-6-7-11)19(20,21)22;1-8-6-12(25-5-4-11(17)24-25)22-14-10(7-21-26(8)14)15(27)23-13(9-2-3-9)16(18,19)20/h4-5,7,10-11,14-16H,3,6,8-9,12-13H2,1-2H3,(H,26,29);2-4,7-9,11,17H,5-6H2,1H3,(H,27,29);4-6,9-11,13-15H,7-8H2,1-3H3,(H,23,26);8-10,12,15H,4-7H2,1-3H3,(H,25,29);3-5,8-9,11,16H,6-7H2,1-2H3,(H,26,28);4-7,9,13H,2-3H2,1H3,(H,23,27)
InChIKeyACOLEDGYFACYBX-UHFFFAOYSA-N
XLogP20.12
TPSA471.04 Ų
H-Bond Donors6
H-Bond Acceptors33
Rotatable Bonds28
Heavy Atoms171
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002382.90
LogP ≤ 520.12
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1033

Analyze 5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide with MolForge

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Related Compounds

2-(1,3-benzodioxol-5-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(1,3-benzodioxol-5-yl)-4-methyl-N-(1,1,1-trifluoropropan-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(1,3-benzoxazol-5-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(1,3-benzoxazol-5-yl)-4-methyl-N-(1,1,1-trifluoropropan-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-chloropyrazol-1-yl)-4-methyl-N-(1,1,1-trifluoropropan-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(5-fluoro-2-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(3-fluoro-4-methylphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide
CID 157651043
2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide
CID 158191746
azetidin-1-yl-[3-(2,2-difluoro-1,3-benzodioxol-5-yl)imidazo[1,2-b]pyridazin-2-yl]methanone;3-(1,3-benzoxazol-6-yl)-N-cyclopropylimidazo[1,2-b]pyridazine-2-carboxamide;3-(4-chlorophenyl)-N-ethylimidazo[1,2-b]pyridazine-2-carboxamide;N-cyclopropyl-3-[6-(difluoromethoxy)-3-pyridinyl]imidazo[1,2-b]pyridazine-2-carboxamide
CID 158728373
2-(1,3-benzoxazol-7-yl)-N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(1,3-benzoxazol-7-yl)-N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropylethyl)-2-(6-cyclopropyloxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(2-oxo-3-propan-2-ylimidazolidin-1-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-2-(3-fluorophenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-methoxyphenyl)-4-methyl-N-[(2R)-1,1,1-trifluoropropan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide
CID 158900408
N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-(3-ethynyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide
CID 160442892
N-(5-chloro-3-cyclopropylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide
CID 161099102
CID 161348184
CID 161348184
benzyl 3-[3-cyclopropyl-7-(pyridine-3-carbonylamino)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylate;benzyl 4-[3-cyclopropyl-7-(pyridine-3-carbonylamino)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylate;N-[5-chloro-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-(3-ethynyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyridine-3-carboxamide;N-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide
CID 161713726
5-(1,3-benzoxazol-5-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(6-carbamoyl-2-pyridinyl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropylethyl]-5-(6-fluoro-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 163641423
N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(5-isocyano-2-methylfuran-3-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(5-isocyano-2-methylfuran-3-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3-isocyano-5-methylfuran-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(5-isocyano-2-methylfuran-3-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-methyl-1,3-oxazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 163670881
N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-8-methyl-6-(1-methylbenzimidazol-5-yl)imidazo[1,2-b]pyridazine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-8-methyl-6-(1-methylbenzimidazol-5-yl)imidazo[1,2-b]pyridazine-3-carboxamide;bis(N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-8-methyl-6-(5-methyl-3-pyridinyl)imidazo[1,2-b]pyridazine-3-carboxamide);bis(N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-8-methyl-6-(5-methyl-3-pyridinyl)imidazo[1,2-b]pyridazine-3-carboxamide);6-(3-isocyano-5-methylfuran-2-yl)-8-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]imidazo[1,2-b]pyridazine-3-carboxamide
CID 163699135
N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(2,5-dimethyl-1,3-oxazol-4-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-5-(4,5-dimethyl-1,3-oxazol-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-methyl-2-propan-2-yl-1,3-oxazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 163709947

Frequently Asked Questions

What is the IUPAC name of 5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The IUPAC name of 5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 163413630) is 5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.
What is the SMILES notation for 5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The canonical SMILES for 5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is CCc1cc(-c2ccccn2)nc2c(C(=O)NC(C)C3CC4(CCC4)C3)cnn12.COc1cccc(-c2cc(C)n3ncc(C(=O)NC(C4CC4)C(F)(F)F)c3n2)n1.Cc1cc(-c2cccc3ncoc23)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2ccccn2)nc2c(C(=O)NC(C)C(C)C3CC3)cnn12.Cc1cc(-n2ccc(Cl)n2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12.Cc1cc(N2CCN(C(C)C)C2=O)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12.
What is the InChIKey of 5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The InChIKey is ACOLEDGYFACYBX-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H27N5O.C20H16F3N5O2.C20H23N5O.C19H23F3N6O2.C19H18F3N5O2.C16H14ClF3N6O/c1-3-17-11-20(19-7-4-5-10-24-19)27-21-18(14-25-28(17)21)22(29)26-15(2)16-12-23(13-16)8-6-9-23;1-10-7-15(12-3-2-4-14-16(12)30-9-24-14)26-18-13(8-25-28(10)18)19(29)27-17(11-5-6-11)20(21,22)23;1-12-10-18(17-6-4-5-9-21-17)24-19-16(11-22-25(12)19)20(26)23-14(3)13(2)15-7-8-15;1-10(2)26-6-7-27(18(26)30)14-8-11(3)28-16(24-14)13(9-23-28)17(29)25-15(12-4-5-12)19(20,21)22;1-10-8-14(13-4-3-5-15(24-13)29-2)25-17-12(9-23-27(10)17)18(28)26-16(11-6-7-11)19(20,21)22;1-8-6-12(25-5-4-11(17)24-25)22-14-10(7-21-26(8)14)15(27)23-13(9-2-3-9)16(18,19)20/h4-5,7,10-11,14-16H,3,6,8-9,12-13H2,1-2H3,(H,26,29);2-4,7-9,11,17H,5-6H2,1H3,(H,27,29);4-6,9-11,13-15H,7-8H2,1-3H3,(H,23,26);8-10,12,15H,4-7H2,1-3H3,(H,25,29);3-5,8-9,11,16H,6-7H2,1-2H3,(H,26,28);4-7,9,13H,2-3H2,1H3,(H,23,27).
What are the key properties of 5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 2382.90 g/mol, XLogP of 20.12, 28 rotatable bonds, 6 hydrogen bond donors, and 33 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(1,3-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3-chloropyrazol-1-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(3-cyclopropylbutan-2-yl)-7-methyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-methoxy-2-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(2-oxo-3-propan-2-ylimidazolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;7-ethyl-5-pyridin-2-yl-N-(1-spiro[3.3]heptan-2-ylethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 163413630), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).