2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide

C26H25N5O4 — CID 16730090

IUPAC2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide
SMILESCOc1cc2ncnc(Oc3ccc(CC(=O)Nc4ccc5c(c4)NCCC5)nc3)c2cc1OC
InChIInChI=1S/C26H25N5O4/c1-33-23-12-20-22(13-24(23)34-2)29-15-30-26(20)35-19-8-7-17(28-14-19)11-25(32)31-18-6-5-16-4-3-9-27-21(16)10-18/h5-8,10,12-15,27H,3-4,9,11H2,1-2H3,(H,31,32)
InChIKeyDWIZWAAPVUQHND-UHFFFAOYSA-N
MW471.52 g/mol
LogP4.37
Rot. Bonds7

About 2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide

2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide (PubChem CID 16730090) has the molecular formula C26H25N5O4 and a molecular weight of 471.52 g/mol. Its IUPAC name is 2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide.

Molecular Properties

Compound Name2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide
PubChem CID16730090
Molecular FormulaC26H25N5O4
Molecular Weight471.52 g/mol
Exact Mass471.19
IUPAC Name2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide
SMILESCOc1cc2ncnc(Oc3ccc(CC(=O)Nc4ccc5c(c4)NCCC5)nc3)c2cc1OC
InChIInChI=1S/C26H25N5O4/c1-33-23-12-20-22(13-24(23)34-2)29-15-30-26(20)35-19-8-7-17(28-14-19)11-25(32)31-18-6-5-16-4-3-9-27-21(16)10-18/h5-8,10,12-15,27H,3-4,9,11H2,1-2H3,(H,31,32)
InChIKeyDWIZWAAPVUQHND-UHFFFAOYSA-N
XLogP4.37
TPSA107.49 Ų
H-Bond Donors2
H-Bond Acceptors8
Rotatable Bonds7
Heavy Atoms35
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500471.52
LogP ≤ 54.37
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 108

Analyze 2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-(2,3-dihydro-1H-indol-6-yl)-2-[4-[6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]oxypyrazol-1-yl]acetamide
CID 69081279
2-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-N-(3-methoxyphenyl)acetamide
CID 57396557
ethyl N-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]carbamate
CID 54582388
1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-methoxyphenyl)urea
CID 22667241
2-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-N-(3-propan-2-yl-1,2-oxazol-5-yl)acetamide
CID 66906894
2-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-N-(4-methoxyphenyl)-2-oxoacetamide
CID 155671308
N-[3-[(cyclopropylamino)methyl]-5-methoxyphenyl]-2-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]acetamide
CID 66907457
tert-butyl 6-[[2-[4-(6,7-dimethoxyquinazolin-4-yl)oxypyrazol-1-yl]acetyl]amino]-2,3-dihydroindole-1-carboxylate
CID 69077685
2-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]acetyl chloride
CID 86238128
2-(2-hydroxyphenyl)-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide
CID 80722972
1-(3-chloro-4-fluorophenyl)-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]urea
CID 54586238
1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(5-methyl-1,2-oxazol-3-yl)urea
CID 22637143

Frequently Asked Questions

What is the IUPAC name of 2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide?
The IUPAC name of 2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide (CID 16730090) is 2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide.
What is the SMILES notation for 2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide?
The canonical SMILES for 2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide is COc1cc2ncnc(Oc3ccc(CC(=O)Nc4ccc5c(c4)NCCC5)nc3)c2cc1OC.
What is the InChIKey of 2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide?
The InChIKey is DWIZWAAPVUQHND-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H25N5O4/c1-33-23-12-20-22(13-24(23)34-2)29-15-30-26(20)35-19-8-7-17(28-14-19)11-25(32)31-18-6-5-16-4-3-9-27-21(16)10-18/h5-8,10,12-15,27H,3-4,9,11H2,1-2H3,(H,31,32).
What are the key properties of 2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide?
2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide has a molecular weight of 471.52 g/mol, XLogP of 4.37, 7 rotatable bonds, 2 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[5-(6,7-dimethoxyquinazolin-4-yl)oxy-2-pyridinyl]-N-(1,2,3,4-tetrahydroquinolin-7-yl)acetamide is sourced from PubChem (CID 16730090), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).