N-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide

C16H15FN4O2S — CID 167920493

IUPACN-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide
SMILESN#Cc1ccc(-c2ncccc2NC(=O)N2CCC(O)C(F)C2)s1
InChIInChI=1S/C16H15FN4O2S/c17-11-9-21(7-5-13(11)22)16(23)20-12-2-1-6-19-15(12)14-4-3-10(8-18)24-14/h1-4,6,11,13,22H,5,7,9H2,(H,20,23)
InChIKeyXFDXAMBZHUSWOL-UHFFFAOYSA-N
MW346.39 g/mol
LogP2.62
Rot. Bonds2

About N-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide

N-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide (PubChem CID 167920493) has the molecular formula C16H15FN4O2S and a molecular weight of 346.39 g/mol. Its IUPAC name is N-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide.

Molecular Properties

Compound NameN-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide
PubChem CID167920493
Molecular FormulaC16H15FN4O2S
Molecular Weight346.39 g/mol
Exact Mass346.09
IUPAC NameN-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide
SMILESN#Cc1ccc(-c2ncccc2NC(=O)N2CCC(O)C(F)C2)s1
InChIInChI=1S/C16H15FN4O2S/c17-11-9-21(7-5-13(11)22)16(23)20-12-2-1-6-19-15(12)14-4-3-10(8-18)24-14/h1-4,6,11,13,22H,5,7,9H2,(H,20,23)
InChIKeyXFDXAMBZHUSWOL-UHFFFAOYSA-N
XLogP2.62
TPSA89.25 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds2
Heavy Atoms24
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500346.39
LogP ≤ 52.62
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

Analyze N-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

1-[[2-(5-methylthiophen-2-yl)-3-pyridinyl]carbamoyl]piperidine-3-carboxylic acid
CID 122090928
(1R)-7,7-dimethyl-N-[2-(5-methylthiophen-2-yl)-3-pyridinyl]-1-oxo-1,4-thiazepane-4-carboxamide
CID 164630602
N-(2-methoxy-3-pyridinyl)-3-methylpiperidine-1-carboxamide
CID 47042573
(3S)-1-N-(2-piperidin-1-yl-3-pyridinyl)pyrrolidine-1,3-dicarboxamide
CID 95580121
(3aR,6aR)-N-[2-(2,2-difluoroethoxy)-3-pyridinyl]-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-carboxamide
CID 136582536
1-N-(2-methoxy-3-pyridinyl)piperidine-1,4-dicarboxamide
CID 47222931
N-(2-fluorophenyl)-3-hydroxypyrrolidine-1-carboxamide
CID 62917965
3-(5-cyanothiophen-2-yl)thieno[2,3-b]pyridine-2-carboxylic acid
CID 139653312
4-methyl-N-(2-pyrrolidin-1-yl-3-pyridinyl)piperidine-1-carboxamide
CID 47041032
(3R)-3-hydroxy-N-(5-pyridin-2-yl-1,3,4-thiadiazol-2-yl)pyrrolidine-1-carboxamide
CID 75467005
(1R,5S)-N-[2-(2-fluorophenoxy)-3-pyridinyl]-7-oxo-3,6-diazabicyclo[3.2.2]nonane-3-carboxamide
CID 118793687
3-(cyclopropylmethoxy)-N-quinolin-8-ylpyrrolidine-1-carboxamide
CID 121022748

Frequently Asked Questions

What is the IUPAC name of N-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide?
The IUPAC name of N-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide (CID 167920493) is N-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide.
What is the SMILES notation for N-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide?
The canonical SMILES for N-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide is N#Cc1ccc(-c2ncccc2NC(=O)N2CCC(O)C(F)C2)s1.
What is the InChIKey of N-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide?
The InChIKey is XFDXAMBZHUSWOL-UHFFFAOYSA-N. The full InChI is InChI=1S/C16H15FN4O2S/c17-11-9-21(7-5-13(11)22)16(23)20-12-2-1-6-19-15(12)14-4-3-10(8-18)24-14/h1-4,6,11,13,22H,5,7,9H2,(H,20,23).
What are the key properties of N-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide?
N-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide has a molecular weight of 346.39 g/mol, XLogP of 2.62, 2 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for N-[2-(5-cyanothiophen-2-yl)-3-pyridinyl]-3-fluoro-4-hydroxypiperidine-1-carboxamide is sourced from PubChem (CID 167920493), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).