6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one

C16H18N2O — CID 170356747

IUPAC6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one
SMILESC=C1NC(=O)CCC1N1c2ccccc2CC12CC2
InChIInChI=1S/C16H18N2O/c1-11-13(6-7-15(19)17-11)18-14-5-3-2-4-12(14)10-16(18)8-9-16/h2-5,13H,1,6-10H2,(H,17,19)
InChIKeyUCGWMLMAJZOTAC-UHFFFAOYSA-N
MW254.33 g/mol
LogP2.37
Rot. Bonds1

About 6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one

6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one (PubChem CID 170356747) has the molecular formula C16H18N2O and a molecular weight of 254.33 g/mol. Its IUPAC name is 6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one.

Molecular Properties

Compound Name6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one
PubChem CID170356747
Molecular FormulaC16H18N2O
Molecular Weight254.33 g/mol
Exact Mass254.14
IUPAC Name6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one
SMILESC=C1NC(=O)CCC1N1c2ccccc2CC12CC2
InChIInChI=1S/C16H18N2O/c1-11-13(6-7-15(19)17-11)18-14-5-3-2-4-12(14)10-16(18)8-9-16/h2-5,13H,1,6-10H2,(H,17,19)
InChIKeyUCGWMLMAJZOTAC-UHFFFAOYSA-N
XLogP2.37
TPSA32.34 Ų
H-Bond Donors1
H-Bond Acceptors2
Rotatable Bonds1
Heavy Atoms19
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500254.33
LogP ≤ 52.37
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 102

Analyze 6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

3-(3-methylidene-1H-isoindol-2-yl)piperidine-2,6-dione
CID 165027847
7-hydroxy-3-methylidene-2-(2-methylidene-6-oxopiperidin-3-yl)isoindol-1-one
CID 163747297
3-spiro[2H-indole-3,4'-piperidine]-1-ylpiperidine-2,6-dione
CID 177175702
3-(4H-1,2,3-benzotriazin-3-yl)piperidine-2,6-dione
CID 170177680
spiro[2,3,3a,5-tetrahydro-1H-pyrrolo[1,2-a]quinoline-4,2'-cyclohexane]-1',3'-dione
CID 11380195
3-(1,3-dihydroisoindol-2-yl)-6-methylidenepiperidin-2-one
CID 170009468
2-(2,6-dioxo(115N)azinan-3-yl)isoindole-1,3-dione
CID 46898665
2-(2,6-dioxo(513C)azinan-3-yl)isoindole-1,3-dione
CID 46898587
2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
CID 161120100
3-(4-propan-2-yl-2,3-dihydroquinoxalin-1-yl)piperidine-2,6-dione
CID 170625595
(3'aR)-spiro[1,3-diazinane-5,4'-2,3,3a,5-tetrahydro-1H-pyrrolo[1,2-a]quinoline]-2,4,6-trione
CID 2037810
3-(2-hydroxy-2H-1,3-benzoxazol-3-yl)piperidine-2,6-dione
CID 166994674

Frequently Asked Questions

What is the IUPAC name of 6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one?
The IUPAC name of 6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one (CID 170356747) is 6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one.
What is the SMILES notation for 6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one?
The canonical SMILES for 6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one is C=C1NC(=O)CCC1N1c2ccccc2CC12CC2.
What is the InChIKey of 6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one?
The InChIKey is UCGWMLMAJZOTAC-UHFFFAOYSA-N. The full InChI is InChI=1S/C16H18N2O/c1-11-13(6-7-15(19)17-11)18-14-5-3-2-4-12(14)10-16(18)8-9-16/h2-5,13H,1,6-10H2,(H,17,19).
What are the key properties of 6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one?
6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one has a molecular weight of 254.33 g/mol, XLogP of 2.37, 1 rotatable bonds, 1 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for 6-methylidene-5-spiro[3H-indole-2,1'-cyclopropane]-1-ylpiperidin-2-one is sourced from PubChem (CID 170356747), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).