N-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide

C17H21F2N3O4 — CID 2436781

IUPACN-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide
SMILESCC(C)C[C@@]1(C)NC(=O)N(CC(=O)Nc2ccc(OC(F)F)cc2)C1=O
InChIInChI=1S/C17H21F2N3O4/c1-10(2)8-17(3)14(24)22(16(25)21-17)9-13(23)20-11-4-6-12(7-5-11)26-15(18)19/h4-7,10,15H,8-9H2,1-3H3,(H,20,23)(H,21,25)/t17-/m1/s1
InChIKeyNGHWOPCMAQCRFH-QGZVFWFLSA-N
MW369.37 g/mol
LogP2.58
Rot. Bonds7

About N-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide

N-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide (PubChem CID 2436781) has the molecular formula C17H21F2N3O4 and a molecular weight of 369.37 g/mol. Its IUPAC name is N-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide.

Molecular Properties

Compound NameN-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide
PubChem CID2436781
Molecular FormulaC17H21F2N3O4
Molecular Weight369.37 g/mol
Exact Mass369.15
IUPAC NameN-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide
SMILESCC(C)C[C@@]1(C)NC(=O)N(CC(=O)Nc2ccc(OC(F)F)cc2)C1=O
InChIInChI=1S/C17H21F2N3O4/c1-10(2)8-17(3)14(24)22(16(25)21-17)9-13(23)20-11-4-6-12(7-5-11)26-15(18)19/h4-7,10,15H,8-9H2,1-3H3,(H,20,23)(H,21,25)/t17-/m1/s1
InChIKeyNGHWOPCMAQCRFH-QGZVFWFLSA-N
XLogP2.58
TPSA87.74 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds7
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500369.37
LogP ≤ 52.58
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'hydantoin', 'substructure': 'N/A'}

Analyze N-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[4-(difluoromethoxy)phenyl]-2-[4-methyl-4-(3-methylbutyl)-2,5-dioxoimidazolidin-1-yl]acetamide
CID 4804583
2-[4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]-N-(4-methylphenyl)acetamide
CID 5002767
2-[4-[4-(difluoromethoxy)phenyl]-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(4-fluorophenyl)acetamide
CID 5031590
N-[4-(difluoromethoxy)phenyl]-2-(2,4-dioxo-1,3-diazaspiro[4.7]dodecan-3-yl)acetamide
CID 2409969
N-(4-chlorophenyl)-2-[4-[4-(difluoromethoxy)phenyl]-4-methyl-2,5-dioxoimidazolidin-1-yl]acetamide
CID 42982854
N-(3-fluoro-4-methylphenyl)-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide
CID 2430195
2-[(4S)-4-[4-(difluoromethoxy)phenyl]-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-phenylacetamide
CID 2108493
2-[(4S)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]-N-(4-piperidin-1-ylphenyl)acetamide
CID 51933528
N-(3-methoxyphenyl)-2-[4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide
CID 4306751
2-[4-[4-(difluoromethoxy)phenyl]-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(4-phenoxyphenyl)acetamide
CID 3965161
N-[4-(difluoromethoxy)phenyl]-2-[(5S,9R)-7,7,9-trimethyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl]acetamide
CID 2579576
2-[4-[4-(difluoromethoxy)phenyl]-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(4-sulfamoylphenyl)acetamide
CID 4993844

Frequently Asked Questions

What is the IUPAC name of N-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide?
The IUPAC name of N-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide (CID 2436781) is N-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide.
What is the SMILES notation for N-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide?
The canonical SMILES for N-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide is CC(C)C[C@@]1(C)NC(=O)N(CC(=O)Nc2ccc(OC(F)F)cc2)C1=O.
What is the InChIKey of N-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide?
The InChIKey is NGHWOPCMAQCRFH-QGZVFWFLSA-N. The full InChI is InChI=1S/C17H21F2N3O4/c1-10(2)8-17(3)14(24)22(16(25)21-17)9-13(23)20-11-4-6-12(7-5-11)26-15(18)19/h4-7,10,15H,8-9H2,1-3H3,(H,20,23)(H,21,25)/t17-/m1/s1.
What are the key properties of N-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide?
N-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide has a molecular weight of 369.37 g/mol, XLogP of 2.58, 7 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-(difluoromethoxy)phenyl]-2-[(4R)-4-methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]acetamide is sourced from PubChem (CID 2436781), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).