2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide

C20H18N2O2S — CID 25018995

IUPAC2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide
SMILESO=C(Nc1nccs1)C1(Cc2ccc(O)cc2)Cc2ccccc2C1
InChIInChI=1S/C20H18N2O2S/c23-17-7-5-14(6-8-17)11-20(18(24)22-19-21-9-10-25-19)12-15-3-1-2-4-16(15)13-20/h1-10,23H,11-13H2,(H,21,22,24)
InChIKeyJFJIDJUZQHPUTA-UHFFFAOYSA-N
MW350.44 g/mol
LogP3.82
Rot. Bonds4

About 2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide

2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide (PubChem CID 25018995) has the molecular formula C20H18N2O2S and a molecular weight of 350.44 g/mol. Its IUPAC name is 2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide.

Molecular Properties

Compound Name2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide
PubChem CID25018995
Molecular FormulaC20H18N2O2S
Molecular Weight350.44 g/mol
Exact Mass350.11
IUPAC Name2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide
SMILESO=C(Nc1nccs1)C1(Cc2ccc(O)cc2)Cc2ccccc2C1
InChIInChI=1S/C20H18N2O2S/c23-17-7-5-14(6-8-17)11-20(18(24)22-19-21-9-10-25-19)12-15-3-1-2-4-16(15)13-20/h1-10,23H,11-13H2,(H,21,22,24)
InChIKeyJFJIDJUZQHPUTA-UHFFFAOYSA-N
XLogP3.82
TPSA62.22 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds4
Heavy Atoms25
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500350.44
LogP ≤ 53.82
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

Analyze 2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

(1R,2S)-1-benzyl-6-hydroxy-2-methyl-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide
CID 87670053
(2R)-2-amino-3-(4-hydroxyphenyl)-N-(1,3-thiazol-2-yl)propanamide
CID 104904532
1-(aminomethyl)-N-(1,3-thiazol-2-yl)cycloheptane-1-carboxamide
CID 115443706
3-ethyl-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CID 63140720
1-hydroxy-N-(1,3-thiazol-2-yl)cyclopentane-1-carboxamide
CID 110906941
(2Z)-2-(3,3-dimethyl-2,4-dihydroisoquinolin-1-ylidene)-N-(1,3-thiazol-2-yl)acetamide
CID 6521850
(1S,2R)-6-hydroxy-2-methyl-1-[4-(4-methylphenyl)phenyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide
CID 89128160
4-(methoxymethyl)-N-(1,3-thiazol-2-yl)piperidine-4-carboxamide
CID 114041967
(3Z)-3-(3,3-dimethyl-2,4-dihydroisoquinolin-1-ylidene)-2-oxo-N-(1,3-thiazol-2-yl)propanamide
CID 5296655
cis-(1R,2S)-3-methylidene-1-N,2-N-bis(1,3-thiazol-2-yl)cyclopropane-1,2-dicarboxamide
CID 2313436
15-(fluoromethyl)-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaene-15-carboxamide
CID 89105368
6-iodo-2-methyl-1-phenyl-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide
CID 76581944

Frequently Asked Questions

What is the IUPAC name of 2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide?
The IUPAC name of 2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide (CID 25018995) is 2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide.
What is the SMILES notation for 2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide?
The canonical SMILES for 2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide is O=C(Nc1nccs1)C1(Cc2ccc(O)cc2)Cc2ccccc2C1.
What is the InChIKey of 2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide?
The InChIKey is JFJIDJUZQHPUTA-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H18N2O2S/c23-17-7-5-14(6-8-17)11-20(18(24)22-19-21-9-10-25-19)12-15-3-1-2-4-16(15)13-20/h1-10,23H,11-13H2,(H,21,22,24).
What are the key properties of 2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide?
2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide has a molecular weight of 350.44 g/mol, XLogP of 3.82, 4 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[(4-hydroxyphenyl)methyl]-N-(1,3-thiazol-2-yl)-1,3-dihydroindene-2-carboxamide is sourced from PubChem (CID 25018995), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).