6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide

C18H24F3N3O3 — CID 39620759

IUPAC6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide
SMILESO=C(N[C@@H]1CCC[C@@H](OCC(F)(F)F)C1)c1ccc(N2CCOCC2)nc1
InChIInChI=1S/C18H24F3N3O3/c19-18(20,21)12-27-15-3-1-2-14(10-15)23-17(25)13-4-5-16(22-11-13)24-6-8-26-9-7-24/h4-5,11,14-15H,1-3,6-10,12H2,(H,23,25)/t14-,15-/m1/s1
InChIKeyVLRIECKIHCTGNI-HUUCEWRRSA-N
MW387.40 g/mol
LogP2.54
Rot. Bonds5

About 6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide

6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide (PubChem CID 39620759) has the molecular formula C18H24F3N3O3 and a molecular weight of 387.40 g/mol. Its IUPAC name is 6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide.

Molecular Properties

Compound Name6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide
PubChem CID39620759
Molecular FormulaC18H24F3N3O3
Molecular Weight387.40 g/mol
Exact Mass387.18
IUPAC Name6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide
SMILESO=C(N[C@@H]1CCC[C@@H](OCC(F)(F)F)C1)c1ccc(N2CCOCC2)nc1
InChIInChI=1S/C18H24F3N3O3/c19-18(20,21)12-27-15-3-1-2-14(10-15)23-17(25)13-4-5-16(22-11-13)24-6-8-26-9-7-24/h4-5,11,14-15H,1-3,6-10,12H2,(H,23,25)/t14-,15-/m1/s1
InChIKeyVLRIECKIHCTGNI-HUUCEWRRSA-N
XLogP2.54
TPSA63.69 Ų
H-Bond Donors1
H-Bond Acceptors5
Rotatable Bonds5
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500387.40
LogP ≤ 52.54
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 105

Analyze 6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide with MolForge

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Related Compounds

6-morpholin-4-yl-N-(2,2,2-trifluoroethyl)pyridine-3-carboxamide
CID 18142338
N-[(3R)-1-methylpyrrolidin-3-yl]-6-morpholin-4-ylpyridine-3-carboxamide
CID 59818085
N-(1-methylpyrrolidin-3-yl)-6-morpholin-4-ylpyridine-3-carboxamide
CID 72570198
cis-(1S,3R)-3-[[6-(azepan-1-yl)pyridine-3-carbonyl]amino]cyclopentane-1-carboxylic acid
CID 120675336
6-(azepan-1-yl)-N-[(3S,5S)-3,5-bis(trifluoromethyl)cyclohexyl]pyridine-3-carboxamide
CID 37319301
N-[(1R,8aR)-1,2,3,5,6,7,8,8a-octahydroindolizin-1-yl]-6-morpholin-4-ylpyridine-3-carboxamide
CID 51724704
6-morpholin-4-yl-N-[[(2S)-oxolan-2-yl]methyl]pyridine-3-carboxamide
CID 724881
6-oxo-N-[3-(2,2,2-trifluoroethoxy)cyclohexyl]-1H-pyridazine-3-carboxamide
CID 42957235
N-[(3S,7S,8aS)-3-cyclopropyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-7-yl]-6-morpholin-4-ylpyridine-3-carboxamide
CID 154818693
4-(trifluoromethyl)-N-[1-[5-(trifluoromethyl)-2-pyridinyl]piperidin-4-yl]benzamide
CID 46475049
N'-(4-fluorobenzoyl)-6-morpholin-4-ylpyridine-3-carbohydrazide
CID 46697479
N-[2-[(2S)-1-methylpiperidin-2-yl]ethyl]-6-morpholin-4-ylpyridine-3-carboxamide
CID 25367128

Frequently Asked Questions

What is the IUPAC name of 6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide?
The IUPAC name of 6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide (CID 39620759) is 6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide.
What is the SMILES notation for 6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide?
The canonical SMILES for 6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide is O=C(N[C@@H]1CCC[C@@H](OCC(F)(F)F)C1)c1ccc(N2CCOCC2)nc1.
What is the InChIKey of 6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide?
The InChIKey is VLRIECKIHCTGNI-HUUCEWRRSA-N. The full InChI is InChI=1S/C18H24F3N3O3/c19-18(20,21)12-27-15-3-1-2-14(10-15)23-17(25)13-4-5-16(22-11-13)24-6-8-26-9-7-24/h4-5,11,14-15H,1-3,6-10,12H2,(H,23,25)/t14-,15-/m1/s1.
What are the key properties of 6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide?
6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide has a molecular weight of 387.40 g/mol, XLogP of 2.54, 5 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 6-morpholin-4-yl-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]pyridine-3-carboxamide is sourced from PubChem (CID 39620759), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).