4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide

C13H15F3N2O2 — CID 4251973

IUPAC4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide
SMILESO=C(Nc1cccc(C(F)(F)F)c1)N1CCC(O)CC1
InChIInChI=1S/C13H15F3N2O2/c14-13(15,16)9-2-1-3-10(8-9)17-12(20)18-6-4-11(19)5-7-18/h1-3,8,11,19H,4-7H2,(H,17,20)
InChIKeyWFFOGVUXQOVCJE-UHFFFAOYSA-N
MW288.27 g/mol
LogP2.69
Rot. Bonds1

About 4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide

4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide (PubChem CID 4251973) has the molecular formula C13H15F3N2O2 and a molecular weight of 288.27 g/mol. Its IUPAC name is 4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide.

Molecular Properties

Compound Name4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide
PubChem CID4251973
Molecular FormulaC13H15F3N2O2
Molecular Weight288.27 g/mol
Exact Mass288.11
IUPAC Name4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide
SMILESO=C(Nc1cccc(C(F)(F)F)c1)N1CCC(O)CC1
InChIInChI=1S/C13H15F3N2O2/c14-13(15,16)9-2-1-3-10(8-9)17-12(20)18-6-4-11(19)5-7-18/h1-3,8,11,19H,4-7H2,(H,17,20)
InChIKeyWFFOGVUXQOVCJE-UHFFFAOYSA-N
XLogP2.69
TPSA52.57 Ų
H-Bond Donors2
H-Bond Acceptors2
Rotatable Bonds1
Heavy Atoms20
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500288.27
LogP ≤ 52.69
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 102

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Related Compounds

N,4-bis[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide
CID 162535440
N-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide
CID 22614394
2-(4-hydroxypiperidin-1-yl)-N-[3-(trifluoromethyl)phenyl]acetamide
CID 31480654
3-acetamido-N-[3-(trifluoromethyl)phenyl]pyrrolidine-1-carboxamide
CID 72862706
4-(propan-2-ylsulfonylamino)-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide
CID 20628883
4-(4-hydroxyphenyl)-N-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide
CID 4129039
3-(methylamino)-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide
CID 62536564
3-(benzenesulfonyl)-N-[3-(trifluoromethyl)phenyl]pyrrolidine-1-carboxamide
CID 71805623
1-N-[3-(trifluoromethyl)phenyl]piperidine-1,3-dicarboxamide
CID 5297464
ethyl 4-[[3-(trifluoromethyl)phenyl]carbamoyl]piperazine-1-carboxylate
CID 3784054
4-ethyl-N-[3-(trifluoromethyl)phenyl]piperazin-4-ium-1-carboxamide
CID 7165092
N-phenyl-4-[3-(trifluoromethyl)phenoxy]piperidine-1-carboxamide
CID 12999550

Frequently Asked Questions

What is the IUPAC name of 4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide?
The IUPAC name of 4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide (CID 4251973) is 4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide.
What is the SMILES notation for 4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide?
The canonical SMILES for 4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide is O=C(Nc1cccc(C(F)(F)F)c1)N1CCC(O)CC1.
What is the InChIKey of 4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide?
The InChIKey is WFFOGVUXQOVCJE-UHFFFAOYSA-N. The full InChI is InChI=1S/C13H15F3N2O2/c14-13(15,16)9-2-1-3-10(8-9)17-12(20)18-6-4-11(19)5-7-18/h1-3,8,11,19H,4-7H2,(H,17,20).
What are the key properties of 4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide?
4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide has a molecular weight of 288.27 g/mol, XLogP of 2.69, 1 rotatable bonds, 2 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for 4-hydroxy-N-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide is sourced from PubChem (CID 4251973), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).