N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide

C23H15F4N5O3 — CID 71010107

IUPACN-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide
SMILESCc1ccncc1C(=O)Nc1cnc(-c2cc(Oc3ncccc3F)ccc2OC(F)(F)F)cn1
InChIInChI=1S/C23H15F4N5O3/c1-13-6-8-28-10-16(13)21(33)32-20-12-30-18(11-31-20)15-9-14(4-5-19(15)35-23(25,26)27)34-22-17(24)3-2-7-29-22/h2-12H,1H3,(H,31,32,33)
InChIKeyYSXVBGHLHGLISM-UHFFFAOYSA-N
MW485.40 g/mol
LogP5.32
Rot. Bonds6

About N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide

N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide (PubChem CID 71010107) has the molecular formula C23H15F4N5O3 and a molecular weight of 485.40 g/mol. Its IUPAC name is N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide.

Molecular Properties

Compound NameN-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide
PubChem CID71010107
Molecular FormulaC23H15F4N5O3
Molecular Weight485.40 g/mol
Exact Mass485.11
IUPAC NameN-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide
SMILESCc1ccncc1C(=O)Nc1cnc(-c2cc(Oc3ncccc3F)ccc2OC(F)(F)F)cn1
InChIInChI=1S/C23H15F4N5O3/c1-13-6-8-28-10-16(13)21(33)32-20-12-30-18(11-31-20)15-9-14(4-5-19(15)35-23(25,26)27)34-22-17(24)3-2-7-29-22/h2-12H,1H3,(H,31,32,33)
InChIKeyYSXVBGHLHGLISM-UHFFFAOYSA-N
XLogP5.32
TPSA99.12 Ų
H-Bond Donors1
H-Bond Acceptors7
Rotatable Bonds6
Heavy Atoms35
Complexity—

Lipinski Rule of Five

1 violation

RuleValue
MW ≤ 500485.40
LogP ≤ 55.32
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 107

Analyze N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[5-[2-chloro-5-[[6-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide
CID 71010141
2-[5-[2-chloro-5-[(3-fluoro-2-pyridinyl)oxy]phenyl]pyrazin-2-yl]-1-(4-methyl-3-pyridinyl)ethanone
CID 149184392
N-[5-(2-ethyl-5-methoxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide
CID 126722767
N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide
CID 70978019
1-(5-fluoro-4-methyl-3-pyridinyl)-2-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-methylphenyl]pyrazin-2-yl]ethanone
CID 146859557
3-fluoro-N-[5-[2-methyl-5-(trifluoromethyl)phenyl]pyrazin-2-yl]pyridine-4-carboxamide
CID 58683977
N-[5-[2-ethoxy-5-(1-imino-3-methyliminopropan-2-yl)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide
CID 123242028
5-fluoro-4-methyl-N-[5-[2-methyl-5-(pyrimidin-2-ylamino)phenyl]pyrazin-2-yl]pyridine-3-carboxamide
CID 90224957
N-[5-[5-[(3Z)-4-aminooxypenta-1,3-dien-2-yl]oxy-2-ethylphenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide
CID 89184659
4-methyl-N-[5-[2-methyl-5-(2-methyl-1,3-thiazol-4-yl)phenyl]pyrazin-2-yl]pyridine-3-carboxamide
CID 70979582
N-[5-(4-methyl-3-pyridinyl)pyrazin-2-yl]-3-[(2-morpholin-4-ylacetyl)amino]-4-(trifluoromethoxy)benzamide
CID 118385278
3-(4-methyl-3-pyridinyl)-2-[4-(trifluoromethoxy)phenoxy]pyridine
CID 135246990

Frequently Asked Questions

What is the IUPAC name of N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide?
The IUPAC name of N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide (CID 71010107) is N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide.
What is the SMILES notation for N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide?
The canonical SMILES for N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide is Cc1ccncc1C(=O)Nc1cnc(-c2cc(Oc3ncccc3F)ccc2OC(F)(F)F)cn1.
What is the InChIKey of N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide?
The InChIKey is YSXVBGHLHGLISM-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H15F4N5O3/c1-13-6-8-28-10-16(13)21(33)32-20-12-30-18(11-31-20)15-9-14(4-5-19(15)35-23(25,26)27)34-22-17(24)3-2-7-29-22/h2-12H,1H3,(H,31,32,33).
What are the key properties of N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide?
N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide has a molecular weight of 485.40 g/mol, XLogP of 5.32, 6 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide is sourced from PubChem (CID 71010107), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).