N-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide

C11H9F2NO3S2 — CID 726530

IUPACN-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide
SMILESO=S(=O)(Nc1ccc(OC(F)F)cc1)c1cccs1
InChIInChI=1S/C11H9F2NO3S2/c12-11(13)17-9-5-3-8(4-6-9)14-19(15,16)10-2-1-7-18-10/h1-7,11,14H
InChIKeyFNFOTOZOKGSXRV-UHFFFAOYSA-N
MW305.33 g/mol
LogP3.15
Rot. Bonds5

About N-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide

N-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide (PubChem CID 726530) has the molecular formula C11H9F2NO3S2 and a molecular weight of 305.33 g/mol. Its IUPAC name is N-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide.

Molecular Properties

Compound NameN-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide
PubChem CID726530
Molecular FormulaC11H9F2NO3S2
Molecular Weight305.33 g/mol
Exact Mass305.00
IUPAC NameN-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide
SMILESO=S(=O)(Nc1ccc(OC(F)F)cc1)c1cccs1
InChIInChI=1S/C11H9F2NO3S2/c12-11(13)17-9-5-3-8(4-6-9)14-19(15,16)10-2-1-7-18-10/h1-7,11,14H
InChIKeyFNFOTOZOKGSXRV-UHFFFAOYSA-N
XLogP3.15
TPSA55.40 Ų
H-Bond Donors1
H-Bond Acceptors4
Rotatable Bonds5
Heavy Atoms19
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500305.33
LogP ≤ 53.15
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 104

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Related Compounds

Rwj-63556
CID 9882374
N-(2-methoxyphenyl)thiophene-2-sulfonamide
CID 738157
4-[(4-Methoxyphenyl)sulfamoyl]thiophene-2-carboxamide
CID 6486042
N-(4-methoxyphenyl)-4-(methylthio)benzenesulfonamide
CID 973953
N-(2,4-dimethoxyphenyl)thiophene-2-sulfonamide
CID 765893
N-{4-[(4-methoxyphenyl)sulfamoyl]phenyl}thiophene-2-sulfonamide
CID 1092869
N-(2-ethoxyphenyl)thiophene-2-sulfonamide
CID 2053786
N-(3-methoxyphenyl)-2,5-dimethylthiophene-3-sulfonamide
CID 1263332
N-acetyl-N-(4-methoxyphenyl)-2-thiophenesulfonamide
CID 701367
N-{4-[(4-ethoxyphenyl)sulfamoyl]phenyl}thiophene-2-sulfonamide
CID 2176514
4-({[4-(Trifluoromethoxy)phenyl]amino}sulfonyl)thiophene-2-carboxamide
CID 24761575
3-{[(4-Methoxyphenyl)amino]sulfonyl}thiolane-1,1-dione
CID 3737827

Frequently Asked Questions

What is the IUPAC name of N-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide?
The IUPAC name of N-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide (CID 726530) is N-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide.
What is the SMILES notation for N-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide?
The canonical SMILES for N-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide is O=S(=O)(Nc1ccc(OC(F)F)cc1)c1cccs1.
What is the InChIKey of N-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide?
The InChIKey is FNFOTOZOKGSXRV-UHFFFAOYSA-N. The full InChI is InChI=1S/C11H9F2NO3S2/c12-11(13)17-9-5-3-8(4-6-9)14-19(15,16)10-2-1-7-18-10/h1-7,11,14H.
What are the key properties of N-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide?
N-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide has a molecular weight of 305.33 g/mol, XLogP of 3.15, 5 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-(difluoromethoxy)phenyl]thiophene-2-sulfonamide is sourced from PubChem (CID 726530), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).