2-(difluoromethyl)-5-piperidin-4-ylpyrazine

C10H13F2N3 — CID 84679627

IUPAC2-(difluoromethyl)-5-piperidin-4-ylpyrazine
SMILESFC(F)c1cnc(C2CCNCC2)cn1
InChIInChI=1S/C10H13F2N3/c11-10(12)9-6-14-8(5-15-9)7-1-3-13-4-2-7/h5-7,10,13H,1-4H2
InChIKeyLTRHOWQXQLUIHC-UHFFFAOYSA-N
MW213.23 g/mol
LogP1.88
Rot. Bonds2

About 2-(difluoromethyl)-5-piperidin-4-ylpyrazine

2-(difluoromethyl)-5-piperidin-4-ylpyrazine (PubChem CID 84679627) has the molecular formula C10H13F2N3 and a molecular weight of 213.23 g/mol. Its IUPAC name is 2-(difluoromethyl)-5-piperidin-4-ylpyrazine.

Molecular Properties

Compound Name2-(difluoromethyl)-5-piperidin-4-ylpyrazine
PubChem CID84679627
Molecular FormulaC10H13F2N3
Molecular Weight213.23 g/mol
Exact Mass213.11
IUPAC Name2-(difluoromethyl)-5-piperidin-4-ylpyrazine
SMILESFC(F)c1cnc(C2CCNCC2)cn1
InChIInChI=1S/C10H13F2N3/c11-10(12)9-6-14-8(5-15-9)7-1-3-13-4-2-7/h5-7,10,13H,1-4H2
InChIKeyLTRHOWQXQLUIHC-UHFFFAOYSA-N
XLogP1.88
TPSA37.81 Ų
H-Bond Donors1
H-Bond Acceptors3
Rotatable Bonds2
Heavy Atoms15
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500213.23
LogP ≤ 51.88
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 103

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Related Compounds

2-piperidin-4-yl-5-[4-(trifluoromethyl)phenyl]pyrazine
CID 95823573
methyl 4-[(2S)-4-[5-(difluoromethyl)pyrazin-2-yl]piperidin-2-yl]benzoate
CID 170632746
3-piperidin-4-yl-6,7-dihydro-5H-cyclopenta[b]pyrazine
CID 83832289
5-fluoro-4-methoxy-2-piperidin-4-ylpyridine
CID 84677771
2-[(4-methylphenyl)methyl]-5-piperidin-4-ylpyrazine;hydrochloride
CID 118741918
3-(5-piperidin-4-ylpyrazin-2-yl)-1,3-oxazolidin-2-one
CID 110096489
N-(2,2-difluoroethyl)-5-[(3S)-piperidin-3-yl]pyrazin-2-amine
CID 95846721
4-cyclobutyl-6-piperidin-4-ylpyrimidine
CID 83849257
4-(difluoromethyl)-2-pyrrolidin-3-yl-1,3-oxazole
CID 84770649
6-piperidin-4-ylpyridazin-3-amine
CID 117105175
3-(azepan-4-yl)isoquinoline
CID 57157960
N-[(6-methyl-2-pyridinyl)methyl]-5-piperidin-4-ylpyrazin-2-amine
CID 95825480

Frequently Asked Questions

What is the IUPAC name of 2-(difluoromethyl)-5-piperidin-4-ylpyrazine?
The IUPAC name of 2-(difluoromethyl)-5-piperidin-4-ylpyrazine (CID 84679627) is 2-(difluoromethyl)-5-piperidin-4-ylpyrazine.
What is the SMILES notation for 2-(difluoromethyl)-5-piperidin-4-ylpyrazine?
The canonical SMILES for 2-(difluoromethyl)-5-piperidin-4-ylpyrazine is FC(F)c1cnc(C2CCNCC2)cn1.
What is the InChIKey of 2-(difluoromethyl)-5-piperidin-4-ylpyrazine?
The InChIKey is LTRHOWQXQLUIHC-UHFFFAOYSA-N. The full InChI is InChI=1S/C10H13F2N3/c11-10(12)9-6-14-8(5-15-9)7-1-3-13-4-2-7/h5-7,10,13H,1-4H2.
What are the key properties of 2-(difluoromethyl)-5-piperidin-4-ylpyrazine?
2-(difluoromethyl)-5-piperidin-4-ylpyrazine has a molecular weight of 213.23 g/mol, XLogP of 1.88, 2 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(difluoromethyl)-5-piperidin-4-ylpyrazine is sourced from PubChem (CID 84679627), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).