N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide

C19H24N4O3 — CID 91838196

IUPACN-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide
SMILESCOc1ccccc1CCC(=O)N[C@@H]1CCN(c2cnccn2)C[C@H]1O
InChIInChI=1S/C19H24N4O3/c1-26-17-5-3-2-4-14(17)6-7-19(25)22-15-8-11-23(13-16(15)24)18-12-20-9-10-21-18/h2-5,9-10,12,15-16,24H,6-8,11,13H2,1H3,(H,22,25)/t15-,16-/m1/s1
InChIKeyCDHDZHHJWYBEIN-HZPDHXFCSA-N
MW356.43 g/mol
LogP1.17
Rot. Bonds6

About N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide

N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide (PubChem CID 91838196) has the molecular formula C19H24N4O3 and a molecular weight of 356.43 g/mol. Its IUPAC name is N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide.

Molecular Properties

Compound NameN-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide
PubChem CID91838196
Molecular FormulaC19H24N4O3
Molecular Weight356.43 g/mol
Exact Mass356.18
IUPAC NameN-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide
SMILESCOc1ccccc1CCC(=O)N[C@@H]1CCN(c2cnccn2)C[C@H]1O
InChIInChI=1S/C19H24N4O3/c1-26-17-5-3-2-4-14(17)6-7-19(25)22-15-8-11-23(13-16(15)24)18-12-20-9-10-21-18/h2-5,9-10,12,15-16,24H,6-8,11,13H2,1H3,(H,22,25)/t15-,16-/m1/s1
InChIKeyCDHDZHHJWYBEIN-HZPDHXFCSA-N
XLogP1.17
TPSA87.58 Ų
H-Bond Donors2
H-Bond Acceptors6
Rotatable Bonds6
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500356.43
LogP ≤ 51.17
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 106

Analyze N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[(1S,2S)-2-hydroxycyclohexyl]-3-(2-methoxyphenyl)propanamide
CID 104956713
N-[2-(2-methoxyphenyl)ethyl]-2-(4-pyrazin-2-ylpiperazin-1-yl)acetamide
CID 18146911
N-[2-(2-methoxyphenyl)ethyl]-4-pyrazin-2-ylpiperazine-1-carboxamide
CID 33384548
3-(2-methoxyphenyl)-N-(2-methylpiperidin-3-yl)propanamide
CID 120573713
2-(2-methoxyphenyl)-1-(4-pyrazin-2-yl-1,4-diazepan-1-yl)ethanone
CID 138385444
1-(2-methoxyphenyl)-N-[(1-pyrazin-2-ylpiperidin-4-yl)methyl]cyclopropane-1-carboxamide
CID 121109138
3-phenoxy-N-(1-pyrazin-2-ylpiperidin-4-yl)propanamide
CID 118780415
3-(2-methoxyphenyl)-N-(1-pyrazin-2-ylpropan-2-yl)propanamide
CID 91775688
3-(2,4-difluorophenyl)-N-(1-pyrazin-2-ylpiperidin-3-yl)propanamide
CID 90648731
N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(trifluoromethyl)benzamide
CID 91843932
N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-1H-indole-6-carboxamide
CID 91841370
N-[2-(aminomethyl)cyclohexyl]-3-(2-methoxyphenyl)propanamide;hydrochloride
CID 119609653

Frequently Asked Questions

What is the IUPAC name of N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide?
The IUPAC name of N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide (CID 91838196) is N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide.
What is the SMILES notation for N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide?
The canonical SMILES for N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide is COc1ccccc1CCC(=O)N[C@@H]1CCN(c2cnccn2)C[C@H]1O.
What is the InChIKey of N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide?
The InChIKey is CDHDZHHJWYBEIN-HZPDHXFCSA-N. The full InChI is InChI=1S/C19H24N4O3/c1-26-17-5-3-2-4-14(17)6-7-19(25)22-15-8-11-23(13-16(15)24)18-12-20-9-10-21-18/h2-5,9-10,12,15-16,24H,6-8,11,13H2,1H3,(H,22,25)/t15-,16-/m1/s1.
What are the key properties of N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide?
N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide has a molecular weight of 356.43 g/mol, XLogP of 1.17, 6 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(3R,4R)-3-hydroxy-1-pyrazin-2-ylpiperidin-4-yl]-3-(2-methoxyphenyl)propanamide is sourced from PubChem (CID 91838196), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).