Acotiamide
ALIMENTARY TRACT AND METABOLISM
Also known as: acofide, acotiamide HCl, acotiamide hydrochloride, acotiamide hydrochloride hydrate, YM-443, Z-338
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Acotiamide is a drug catalogued in DrugCentral. It was first approved by the PMDA in 2013. DrugCentral lists 1 molecular target, including ACHE. Recorded indications include Nonulcer dyspepsia.
- Molecular targets: ACHE (1 listed in DrugCentral).
- Indications: Nonulcer dyspepsia.
- ATC code: A03FA10 (Propulsives).
- Molecular formula: C21H30N4O5S; molecular weight 450.55 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- Nonulcer dyspepsia
Mechanism & targets
Molecular targets (1)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Acetylcholinesterase | ACHE | inhibitor | IC50 5.52 |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| 2013-03-25 | PMDA | — | Zeria |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
A03FA10 | ALIMENTARY TRACT AND METABOLISM › DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS › PROPULSIVES › Propulsives |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Acotiamide is on its molecule page.
| Molecular formula | C21H30N4O5S |
|---|---|
| Molecular weight | 450.55 g/mol |
| CAS number | 185106-16-5 |
| InChIKey | TWHZNAUBXFZMCA-UHFFFAOYSA-N |
| PubChem CID | 5282338 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Acotiamide used for?
DrugCentral lists the following indications for Acotiamide: Nonulcer dyspepsia.
How does Acotiamide work?
Its molecular targets in DrugCentral include ACHE (inhibitor).
When was Acotiamide first approved?
Acotiamide was first approved by the PMDA in 2013.
What is the chemical formula of Acotiamide?
Acotiamide has the molecular formula C21H30N4O5S and a molecular weight of 450.55 g/mol.
Browse: all drugs starting with A · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 4908 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL2107308 — compound record and bioactivity
- PubChem CID 5282338 — chemical identifiers
- DrugBank DB12482 — drug record
- FDA UNII D42OWK5383 — substance identity
- UniProt P22303 (ACHE) — target protein
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