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Acotiamide

ALIMENTARY TRACT AND METABOLISM

Also known as: acofide, acotiamide HCl, acotiamide hydrochloride, acotiamide hydrochloride hydrate, YM-443, Z-338

PMDA approvedATC A03FA10

Data last refreshed: (DrugCentral release 2024-11-01)

Key facts

Acotiamide is a drug catalogued in DrugCentral. It was first approved by the PMDA in 2013. DrugCentral lists 1 molecular target, including ACHE. Recorded indications include Nonulcer dyspepsia.

  • Molecular targets: ACHE (1 listed in DrugCentral).
  • Indications: Nonulcer dyspepsia.
  • ATC code: A03FA10 (Propulsives).
  • Molecular formula: C21H30N4O5S; molecular weight 450.55 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

  • Nonulcer dyspepsia

Mechanism & targets

Molecular targets (1)

TargetGeneActionActivity
AcetylcholinesteraseACHEinhibitorIC50 5.52

Regulatory approvals (1)

DateAgencyMarketed asApplicantOrphan
2013-03-25PMDA—Zeria

ATC classification

ATC codeTherapeutic hierarchy
A03FA10ALIMENTARY TRACT AND METABOLISM › DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS › PROPULSIVES › Propulsives

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Acotiamide is on its molecule page.

Molecular formulaC21H30N4O5S
Molecular weight450.55 g/mol
CAS number185106-16-5
InChIKeyTWHZNAUBXFZMCA-UHFFFAOYSA-N
PubChem CID5282338
COC1=CC(O)=C(C=C1OC)C(=O)NC1=NC(=CS1)C(=O)NCCN(C(C)C)C(C)C

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Acotiamide used for?

DrugCentral lists the following indications for Acotiamide: Nonulcer dyspepsia.

How does Acotiamide work?

Its molecular targets in DrugCentral include ACHE (inhibitor).

When was Acotiamide first approved?

Acotiamide was first approved by the PMDA in 2013.

What is the chemical formula of Acotiamide?

Acotiamide has the molecular formula C21H30N4O5S and a molecular weight of 450.55 g/mol.

Browse: all drugs starting with A · drug guides by category · protein targets A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

Quick facts

Status—
First approval2013-03-25
AgencyPMDA
Targets1
Indications1
FormulaC21H30N4O5S
DrugCentral ID4908
Interactive profile