Clebopride

ALIMENTARY TRACT AND METABOLISM

Key facts

Clebopride is a drug catalogued in DrugCentral. DrugCentral lists 11 molecular targets, including Drd2, DRD4 and DRD3.

• Molecular targets: Drd2, DRD4, DRD3 and DRD2 (11 listed in DrugCentral).
• ATC code: A03FA06 (Propulsives).
• Molecular formula: C20H24ClN3O2; molecular weight 373.88 g/mol.

Mechanism & targets

Molecular targets (11)

Target	Gene	Action	Activity
D(2) dopamine receptor	Drd2	unknown	Ki 8.95
D(4) dopamine receptor	DRD4	unknown	Ki 8.49
D(3) dopamine receptor	DRD3	unknown	Ki 7.98
D(2) dopamine receptor	DRD2	unknown	Ki 7.92
Serotonin 2 (5-HT2) receptor	Htr2c|Htr2a|Htr2b	unknown	Ki 7.05
5-hydroxytryptamine receptor 4	HTR4	unknown	Ki 6.98
5-hydroxytryptamine receptor 4	Htr4	unknown	Ki 6.98
Adrenergic receptor alpha-2	Adra2b|Adra2c|Adra2a	unknown	Ki 6.22
Potassium voltage-gated channel subfamily H member 2	KCNH2	unknown	IC50 6.22
Acetylcholinesterase	ACHE	unknown	IC50 6.05
D(1A) dopamine receptor	DRD1	unknown	Ki 5.22

ATC classification

ATC code	Therapeutic hierarchy
A03FA06	ALIMENTARY TRACT AND METABOLISM › DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS › PROPULSIVES › Propulsives

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Mixed liver injury	77.2

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Clebopride is on its molecule page.

• Molecular formula: C₂₀H₂₄ClN₃O₂
• Molecular weight: 373.88 g/mol
• CAS number: 55905-53-8
• InChIKey: BVPWJMCABCPUQY-UHFFFAOYSA-N
• PubChem CID: 2780

COC1=C(C=C(Cl)C(N)=C1)C(=O)NC1CCN(CC2=CC=CC=C2)CC1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Clebopride work?

Its molecular targets in DrugCentral include Drd2, DRD4, DRD3 and DRD2.

What is the chemical formula of Clebopride?

Clebopride has the molecular formula C20H24ClN3O2 and a molecular weight of 373.88 g/mol.

Sources

• DrugCentral drug card 670 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1599248 — compound record and bioactivity
• PubChem CID 2780 — chemical identifiers
• DrugBank DB13511 — drug record
• FDA UNII I0A84520Y9 — substance identity
• UniProt P21917 (DRD4) — target protein
• UniProt P35462 (DRD3) — target protein
• UniProt P14416 (DRD2) — target protein
• UniProt Q12809 (KCNH2) — target protein
• UniProt P22303 (ACHE) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.