Aldesulfone

ANTIINFECTIVES FOR SYSTEMIC USE

Key facts

Aldesulfone is an ofm drug catalogued in DrugCentral. It was first approved by the FDA in 1974. DrugCentral lists 2 molecular targets, including folP1 and G6PD.

• Approval status: ofm (first approved 1974 by the FDA).
• Molecular targets: folP1 and G6PD (2 listed in DrugCentral).
• ATC code: J04BA03 (Drugs for treatment of lepra).
• Molecular formula: C14H16N2O6S3; molecular weight 404.47 g/mol.

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Dihydropteroate synthase 1	folP1	inhibitor	—
Glucose-6-phosphate 1-dehydrogenase	G6PD	unknown	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1974-05-24	FDA	—	ABBVIE

ATC classification

ATC code	Therapeutic hierarchy
J04BA03	ANTIINFECTIVES FOR SYSTEMIC USE › ANTIMYCOBACTERIALS › DRUGS FOR TREATMENT OF LEPRA › Drugs for treatment of lepra

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Aldesulfone is on its molecule page.

• Molecular formula: C₁₄H₁₆N₂O₆S₃
• Molecular weight: 404.47 g/mol
• CAS number: 144-75-2
• InChIKey: NEDPPCHNEOMTJV-UHFFFAOYSA-N
• PubChem CID: 5351

OS(=O)CNC1=CC=C(C=C1)S(=O)(=O)C1=CC=C(NCS(O)=O)C=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Aldesulfone work?

Its molecular targets in DrugCentral include folP1 (inhibitor) and G6PD.

When was Aldesulfone first approved?

Aldesulfone was first approved by the FDA in 1974.

What is the chemical formula of Aldesulfone?

Aldesulfone has the molecular formula C14H16N2O6S3 and a molecular weight of 404.47 g/mol.

Sources

• DrugCentral drug card 2533 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1200580 — compound record and bioactivity
• PubChem CID 5351 — chemical identifiers
• DrugBank DB01145 — drug record
• FDA UNII 57OWB0Q221 — substance identity
• DailyMed: FDA labels for Aldesulfone — current prescribing information (label search)
• UniProt P11413 (G6PD) — target protein

How this page is built: methodology · editorial policy & corrections.