Aminophenazone
NERVOUS SYSTEM
Also known as: amidazophen, amidazophene, amidofebrin, amidofen, amidophen, amidophenazone, amidopyrazoline, amidopyrin, amidopyrine, aminophenazon, aminopyrin, aminopyrine
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Aminophenazone is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1964. DrugCentral lists 3 molecular targets, including NAPRT, PTGS2 and PTGS1.
- Molecular targets: NAPRT, PTGS2 and PTGS1 (3 listed in DrugCentral).
- ATC code: N02BB03 (Pyrazolones).
- Molecular formula: C13H17N3O; molecular weight 231.30 g/mol.
Mechanism & targets
Molecular targets (3)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Nicotinate phosphoribosyltransferase | NAPRT | unknown | Ki 9.00 |
| Prostaglandin G/H synthase 2 | PTGS2 | unknown | — |
| Prostaglandin G/H synthase 1 | PTGS1 | unknown | — |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| 1964-01-01 | YEAR INTRODUCED | — | — |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
N02BB03 | NERVOUS SYSTEM › ANALGESICS › OTHER ANALGESICS AND ANTIPYRETICS › Pyrazolones |
N02BB53 | NERVOUS SYSTEM › ANALGESICS › OTHER ANALGESICS AND ANTIPYRETICS › Pyrazolones |
N02BB73 | NERVOUS SYSTEM › ANALGESICS › OTHER ANALGESICS AND ANTIPYRETICS › Pyrazolones |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Aminophenazone is on its molecule page.
| Molecular formula | C13H17N3O |
|---|---|
| Molecular weight | 231.30 g/mol |
| CAS number | 58-15-1 |
| InChIKey | RMMXTBMQSGEXHJ-UHFFFAOYSA-N |
| PubChem CID | 6009 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
How does Aminophenazone work?
Its molecular targets in DrugCentral include NAPRT, PTGS2 and PTGS1.
When was Aminophenazone first approved?
Aminophenazone was first approved by the YEAR INTRODUCED in 1964.
What is the chemical formula of Aminophenazone?
Aminophenazone has the molecular formula C13H17N3O and a molecular weight of 231.30 g/mol.
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Sources
- DrugCentral drug card 171 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL288470 — compound record and bioactivity
- PubChem CID 6009 — chemical identifiers
- DrugBank DB01424 — drug record
- FDA UNII 01704YP3MO — substance identity
- UniProt Q6XQN6 (NAPRT) — target protein
- UniProt P35354 (PTGS2) — target protein
- UniProt P23219 (PTGS1) — target protein
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