Amobarbital
NERVOUS SYSTEM
Also known as: amobarbital sodium, amobarbitone, amylbarbitone, amylobarbital, amylobarbitone, barbamyl acid, ethylisopentylbarbituric acid, isoamylethylbarbituric acid, isopentobarbital
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Amobarbital is a drug catalogued in DrugCentral. Recorded indications include Epilepsy, General anesthesia, Insomnia and Local anesthesia.
- Indications: Epilepsy, General anesthesia, Insomnia, Local anesthesia and Narcoanalysis and others.
- ATC code: N05CA02 (Barbiturates, plain).
- Molecular formula: C11H18N2O3; molecular weight 226.28 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (8)
- Epilepsy
- General anesthesia
- Insomnia
- Local anesthesia
- Narcoanalysis
- Seizure disorder
- Severe anxiety (panic)
- Status epilepticus
Contraindications (28)
- Acute exacerbation of asthma
- Alcoholism
- Anemia
- Apnea
- Chronic obstructive lung disease
- Decreased respiratory function
- Depressive disorder
- Disease of liver
- Disorder of lung
- Heart disease
- Hepatic coma
- Hepatic encephalopathy
- Hepatic failure
- Hyperactive behavior
- Hyperammonemia
- Hypertensive disorder
- Kidney disease
- Low blood pressure
- Neutropenic disorder
- Pneumonia
- Porphyria
- Pregnancy, function
- Respiratory insufficiency
- Sleep apnea
- Sleep automatism
- Substance abuse
- Suicidal thoughts
- Thrombocytopenic disorder
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| — | FDA | — | — |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
N05CA02 | NERVOUS SYSTEM › PSYCHOLEPTICS › HYPNOTICS AND SEDATIVES › Barbiturates, plain |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Amobarbital is on its molecule page.
| Molecular formula | C11H18N2O3 |
|---|---|
| Molecular weight | 226.28 g/mol |
| CAS number | 57-43-2 |
| InChIKey | VIROVYVQCGLCII-UHFFFAOYSA-N |
| PubChem CID | 2164 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Amobarbital used for?
DrugCentral lists the following indications for Amobarbital: Epilepsy, General anesthesia, Insomnia, Local anesthesia, Narcoanalysis, Seizure disorder, Severe anxiety (panic) and Status epilepticus.
What is the chemical formula of Amobarbital?
Amobarbital has the molecular formula C11H18N2O3 and a molecular weight of 226.28 g/mol.
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Sources
- DrugCentral drug card 184 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL2105941 — compound record and bioactivity
- PubChem CID 2164 — chemical identifiers
- DrugBank DB01351 — drug record
- FDA UNII GWH6IJ239E — substance identity
- DailyMed: FDA labels for Amobarbital — current prescribing information (label search)
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