Hexobarbital
NERVOUS SYSTEM
Also known as: barbidorm, hexobarbitone, methexenyl, methylhexabarbital, methylhexabital
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Hexobarbital is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1932. DrugCentral lists 4 molecular targets, including GABRG2|GABRB3|GABRA2, GABRG2|GABRB3|GABRA3 and GABRG2|GABRB3|GABRA5.
- Molecular targets: GABRG2|GABRB3|GABRA2, GABRG2|GABRB3|GABRA3, GABRG2|GABRB3|GABRA5 and GABRA1|GABRG2|GABRB3 (4 listed in DrugCentral).
- ATC code: N01AF02 (Barbiturates, plain).
- Molecular formula: C12H16N2O3; molecular weight 236.27 g/mol.
Mechanism & targets
Molecular targets (4)
| Target | Gene | Action | Activity |
|---|---|---|---|
| GABA-A receptor alpha-2/beta-3/gamma-2 | GABRG2|GABRB3|GABRA2 | unknown | — |
| GABA-A receptor alpha-3/beta-3/gamma-2 | GABRG2|GABRB3|GABRA3 | unknown | — |
| GABA-A receptor alpha-5/beta-3/gamma-2 | GABRG2|GABRB3|GABRA5 | unknown | — |
| GABA-A receptor alpha-1/beta-3/gamma-2 | GABRA1|GABRG2|GABRB3 | unknown | — |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| 1932-01-01 | YEAR INTRODUCED | — | — |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
N01AF02 | NERVOUS SYSTEM › ANESTHETICS › ANESTHETICS, GENERAL › Barbiturates, plain |
N05CA16 | NERVOUS SYSTEM › PSYCHOLEPTICS › HYPNOTICS AND SEDATIVES › Barbiturates, plain |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Hexobarbital is on its molecule page.
| Molecular formula | C12H16N2O3 |
|---|---|
| Molecular weight | 236.27 g/mol |
| CAS number | 56-29-1 |
| InChIKey | UYXAWHWODHRRMR-UHFFFAOYSA-N |
| PubChem CID | 3608 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
How does Hexobarbital work?
Its molecular targets in DrugCentral include GABRG2|GABRB3|GABRA2, GABRG2|GABRB3|GABRA3, GABRG2|GABRB3|GABRA5 and GABRA1|GABRG2|GABRB3.
When was Hexobarbital first approved?
Hexobarbital was first approved by the YEAR INTRODUCED in 1932.
What is the chemical formula of Hexobarbital?
Hexobarbital has the molecular formula C12H16N2O3 and a molecular weight of 236.27 g/mol.
Browse: all drugs starting with H · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 1369 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL7728 — compound record and bioactivity
- PubChem CID 3608 — chemical identifiers
- DrugBank DB01355 — drug record
- FDA UNII AL8Z8K3P6S — substance identity
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.