Azapropazone

MUSCULO-SKELETAL SYSTEM

Key facts

Azapropazone is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1972. DrugCentral lists 2 molecular targets, including PTGS1 and XDH. Recorded indications include Ankylosing spondylitis, Gout, Osteoarthritis and Rheumatoid arthritis.

• Molecular targets: PTGS1 and XDH (2 listed in DrugCentral).
• Indications: Ankylosing spondylitis, Gout, Osteoarthritis and Rheumatoid arthritis.
• ATC code: M01AX04 (Other antiinflammatory and antirheumatic agents, non-steroids).
• Molecular formula: C16H20N4O2; molecular weight 300.36 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (4)

• Ankylosing spondylitis
• Gout
• Osteoarthritis
• Rheumatoid arthritis

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Prostaglandin G/H synthase 1	PTGS1	unknown	—
Xanthine dehydrogenase/oxidase	XDH	unknown	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1972-01-01	YEAR INTRODUCED	—	—

ATC classification

ATC code	Therapeutic hierarchy
M01AX04	MUSCULO-SKELETAL SYSTEM › ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS › ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS › Other antiinflammatory and antirheumatic agents, non-steroids

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Azapropazone is on its molecule page.

• Molecular formula: C₁₆H₂₀N₄O₂
• Molecular weight: 300.36 g/mol
• CAS number: 13539-59-8
• InChIKey: MPHPHYZQRGLTBO-UHFFFAOYSA-N
• PubChem CID: 26098

CCCC1C(=O)N2N(C1=O)C1=CC(C)=CC=C1N=C2N(C)C

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Azapropazone used for?

DrugCentral lists the following indications for Azapropazone: Ankylosing spondylitis, Gout, Osteoarthritis and Rheumatoid arthritis.

How does Azapropazone work?

Its molecular targets in DrugCentral include PTGS1 and XDH.

When was Azapropazone first approved?

Azapropazone was first approved by the YEAR INTRODUCED in 1972.

What is the chemical formula of Azapropazone?

Azapropazone has the molecular formula C16H20N4O2 and a molecular weight of 300.36 g/mol.

Sources

• DrugCentral drug card 266 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1565476 — compound record and bioactivity
• PubChem CID 26098 — chemical identifiers
• DrugBank DB07402 — drug record
• FDA UNII BF18764H96 — substance identity
• UniProt P23219 (PTGS1) — target protein
• UniProt P47989 (XDH) — target protein

How this page is built: methodology · editorial policy & corrections.