Benzydamine
ALIMENTARY TRACT AND METABOLISM
Also known as: benzidamine, benzindamine, benzydamide, benzydamine HCl, benzydamine hydrochloride
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Benzydamine is a drug catalogued in DrugCentral. DrugCentral lists 1 molecular target, including GUCY1B2|GUCY1A2|GUCY1A3|GUCY1B3. Recorded indications include Pain.
- Molecular targets: GUCY1B2|GUCY1A2|GUCY1A3|GUCY1B3 (1 listed in DrugCentral).
- Indications: Pain.
- ATC code: A01AD02 (Other agents for local oral treatment).
- Molecular formula: C19H23N3O; molecular weight 309.41 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- Pain
Mechanism & targets
Molecular targets (1)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Soluble guanylate cyclase | GUCY1B2|GUCY1A2|GUCY1A3|GUCY1B3 | unknown | EC50 5.99 |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
A01AD02 | ALIMENTARY TRACT AND METABOLISM › STOMATOLOGICAL PREPARATIONS › STOMATOLOGICAL PREPARATIONS › Other agents for local oral treatment |
G02CC03 | GENITO URINARY SYSTEM AND SEX HORMONES › OTHER GYNECOLOGICALS › OTHER GYNECOLOGICALS › Antiinflammatory products for vaginal administration |
M01AX07 | MUSCULO-SKELETAL SYSTEM › ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS › ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS › Other antiinflammatory and antirheumatic agents, non-steroids |
M02AA05 | MUSCULO-SKELETAL SYSTEM › TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN › TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN › Antiinflammatory preparations, non-steroids for topical use |
R02AX03 | RESPIRATORY SYSTEM › THROAT PREPARATIONS › THROAT PREPARATIONS › Other throat preparations |
Reported adverse-event signals
Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.
| MedDRA term | LLR |
|---|---|
| Macular degeneration | 483.6 |
| Vaginal flatulence | 457.8 |
| Female genital tract fistula | 422.1 |
| Proctitis | 411.2 |
| Vaginal discharge | 407.3 |
| Chronic sinusitis | 403.1 |
| Radiculopathy | 394.5 |
| Paraesthesia oral | 371.0 |
| Oral candidiasis | 318.4 |
| Procedural pain | 295.3 |
| Frequent bowel movements | 257.1 |
| Rectal haemorrhage | 251.0 |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Benzydamine is on its molecule page.
| Molecular formula | C19H23N3O |
|---|---|
| Molecular weight | 309.41 g/mol |
| CAS number | 642-72-8 |
| InChIKey | CNBGNNVCVSKAQZ-UHFFFAOYSA-N |
| PubChem CID | 12555 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Benzydamine used for?
DrugCentral lists the following indications for Benzydamine: Pain.
How does Benzydamine work?
Its molecular targets in DrugCentral include GUCY1B2|GUCY1A2|GUCY1A3|GUCY1B3.
What is the chemical formula of Benzydamine?
Benzydamine has the molecular formula C19H23N3O and a molecular weight of 309.41 g/mol.
Browse: all drugs starting with B · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 3881 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL12610 — compound record and bioactivity
- PubChem CID 12555 — chemical identifiers
- DrugBank DB09084 — drug record
- FDA UNII 4O21U048EF — substance identity
- FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral
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