Proquazone

MUSCULO-SKELETAL SYSTEM

Key facts

Proquazone is a drug catalogued in DrugCentral. DrugCentral lists 4 molecular targets, including EGFR, PTGS1|PTGS2 and PTGS2.

• Molecular targets: EGFR, PTGS1|PTGS2, PTGS2 and PTGS1 (4 listed in DrugCentral).
• ATC code: M01AX13 (Other antiinflammatory and antirheumatic agents, non-steroids).
• Molecular formula: C18H18N2O; molecular weight 278.36 g/mol.

Mechanism & targets

Molecular targets (4)

Target	Gene	Action	Activity
Epidermal growth factor receptor	EGFR	unknown	IC50 8.70
Cyclooxygenase	PTGS1|PTGS2	unknown	IC50 7.15
Prostaglandin G/H synthase 2	PTGS2	unknown	—
Prostaglandin G/H synthase 1	PTGS1	unknown	—

ATC classification

ATC code	Therapeutic hierarchy
M01AX13	MUSCULO-SKELETAL SYSTEM › ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS › ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS › Other antiinflammatory and antirheumatic agents, non-steroids

Chemical structure

• Molecular formula: C₁₈H₁₈N₂O
• Molecular weight: 278.36 g/mol
• CAS number: 22760-18-5
• InChIKey: JTIGKVIOEQASGT-UHFFFAOYSA-N
• PubChem CID: 31508

CC(C)N1C(=O)N=C(C2=CC=CC=C2)C2=CC=C(C)C=C12

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Proquazone work?

Its molecular targets in DrugCentral include EGFR, PTGS1|PTGS2, PTGS2 and PTGS1.

What is the chemical formula of Proquazone?

Proquazone has the molecular formula C18H18N2O and a molecular weight of 278.36 g/mol.

Sources

• DrugCentral drug card 2311 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL268501 — compound record and bioactivity
• PubChem CID 31508 — chemical identifiers
• DrugBank DB13649 — drug record
• FDA UNII 42VPJ2980S — substance identity
• UniProt P00533 (EGFR) — target protein
• UniProt P35354 (PTGS2) — target protein
• UniProt P23219 (PTGS1) — target protein

How this page is built: methodology · editorial policy & corrections.