Azlocillin

ANTIINFECTIVES FOR SYSTEMIC USE

Key facts

Azlocillin is an ofm drug catalogued in DrugCentral. It was first approved by the FDA in 1982. DrugCentral lists 1 molecular target, including mrcA|pbpB|pbpC|pbpA|dacA|ponB. Recorded indications include Aspiration pneumonia, Bacterial infection due to Klebsiella pneumoniae, Bacterial infection due to Serratia and Bacterial septicemia.

• Approval status: ofm (first approved 1982 by the FDA).
• Molecular targets: mrcA|pbpB|pbpC|pbpA|dacA|ponB (1 listed in DrugCentral).
• Indications: Aspiration pneumonia, Bacterial infection due to Klebsiella pneumoniae, Bacterial infection due to Serratia, Bacterial septicemia and Enterobacter Pneumonia and others.
• ATC code: J01CA09 (Penicillins with extended spectrum).
• Molecular formula: C20H23N5O6S; molecular weight 461.49 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (12)

• Aspiration pneumonia
• Bacterial infection due to Klebsiella pneumoniae
• Bacterial infection due to Serratia
• Bacterial septicemia
• Enterobacter Pneumonia
• Haemophilus influenzae pneumonia
• Infection of bone
• Infection of skin AND/OR subcutaneous tissue
• Infectious disorder of joint
• Pneumonia due to Escherichia coli
• Pneumonia due to Pseudomonas
• Urinary tract infectious disease

Off-label uses (4)

• Abscess of brain
• Cholangitis
• Infectious disease of abdomen
• Pseudomonas Aeruginosa Meningitis

Contraindications (3)

• Infectious mononucleosis
• Kidney disease
• Pseudomembranous enterocolitis

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Penicillin-binding protein	mrcA|pbpB|pbpC|pbpA|dacA|ponB	inhibitor	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1982-09-03	FDA	—	BAYER PHARMACEUTICALS CORP

ATC classification

ATC code	Therapeutic hierarchy
J01CA09	ANTIINFECTIVES FOR SYSTEMIC USE › ANTIBACTERIALS FOR SYSTEMIC USE › BETA-LACTAM ANTIBACTERIALS, PENICILLINS › Penicillins with extended spectrum

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Azlocillin is on its molecule page.

• Molecular formula: C₂₀H₂₃N₅O₆S
• Molecular weight: 461.49 g/mol
• CAS number: 37091-66-0
• InChIKey: JTWOMNBEOCYFNV-NFFDBFGFSA-N
• PubChem CID: 6479523

CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](NC(=O)N3CCNC3=O)C3=CC=CC=C3)C(=O)N2[C@H]1C(O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Azlocillin used for?

DrugCentral lists the following indications for Azlocillin: Aspiration pneumonia, Bacterial infection due to Klebsiella pneumoniae, Bacterial infection due to Serratia, Bacterial septicemia, Enterobacter Pneumonia, Haemophilus influenzae pneumonia, Infection of bone and Infection of skin AND/OR subcutaneous tissue and others.

How does Azlocillin work?

Its molecular targets in DrugCentral include mrcA|pbpB|pbpC|pbpA|dacA|ponB (inhibitor).

When was Azlocillin first approved?

Azlocillin was first approved by the FDA in 1982.

What is the chemical formula of Azlocillin?

Azlocillin has the molecular formula C20H23N5O6S and a molecular weight of 461.49 g/mol.

Sources

• DrugCentral drug card 277 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1201041 — compound record and bioactivity
• PubChem CID 6479523 — chemical identifiers
• DrugBank DB01061 — drug record
• FDA UNII HUM6H389W0 — substance identity
• DailyMed: FDA labels for Azlocillin — current prescribing information (label search)

How this page is built: methodology · editorial policy & corrections.