Carbenicillin

Penicillin-class Antibacterial — ANTIINFECTIVES FOR SYSTEMIC USE

Key facts

Carbenicillin is an ofm drug in the Penicillin-class Antibacterial class catalogued in DrugCentral. DrugCentral lists 4 molecular targets, including CHRM1, CHRM3 and pbpA. Recorded indications include Bacterial urinary infection, Enterobacter Prostatitis, Enterococcus Prostatitis and Enterococcus Urinary Tract Infection.

• Approval status: ofm.
• Drug class: Penicillin-class Antibacterial.
• Molecular targets: CHRM1, CHRM3, pbpA and mrcA|mrcB|dacC|mrdA|ftsI|dacA|dacB (4 listed in DrugCentral).
• Indications: Bacterial urinary infection, Enterobacter Prostatitis, Enterococcus Prostatitis, Enterococcus Urinary Tract Infection and Escherichia coli urinary tract infection and others.
• ATC code: J01CA03 (Penicillins with extended spectrum).
• Molecular formula: C17H18N2O6S; molecular weight 378.40 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (12)

• Bacterial urinary infection
• Enterobacter Prostatitis
• Enterococcus Prostatitis
• Enterococcus Urinary Tract Infection
• Escherichia coli urinary tract infection
• Morganella Morganii Urinary Tract Infection
• Prostatitis
• Proteus Prostatitis
• Proteus urinary tract infection
• Providencia Urinary Tract Infection
• Pseudomonas Aeruginosa Urinary Tract Infection
• Urinary tract infectious disease

Contraindications (3)

• Infectious mononucleosis
• Kidney disease
• Pseudomembranous enterocolitis

Mechanism & targets

• Established pharmacologic class: Penicillin-class Antibacterial

Molecular targets (4)

Target	Gene	Action	Activity
Muscarinic acetylcholine receptor M1	CHRM1	unknown	IC50 5.37
Muscarinic acetylcholine receptor M3	CHRM3	unknown	IC50 5.00
Penicillin-binding protein 1A	pbpA	unknown	—
Bacterial penicillin-binding protein	mrcA|mrcB|dacC|mrdA|ftsI|dacA|dacB	inhibitor	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	ROERIG

ATC classification

ATC code	Therapeutic hierarchy
J01CA03	ANTIINFECTIVES FOR SYSTEMIC USE › ANTIBACTERIALS FOR SYSTEMIC USE › BETA-LACTAM ANTIBACTERIALS, PENICILLINS › Penicillins with extended spectrum

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Carbenicillin is on its molecule page.

• Molecular formula: C₁₇H₁₈N₂O₆S
• Molecular weight: 378.40 g/mol
• CAS number: 4697-36-3
• InChIKey: FPPNZSSZRUTDAP-UWFZAAFLSA-N
• PubChem CID: 20824

CC1(C)S[C@@H]2[C@H](NC(=O)C(C(O)=O)C3=CC=CC=C3)C(=O)N2[C@H]1C(O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Carbenicillin used for?

DrugCentral lists the following indications for Carbenicillin: Bacterial urinary infection, Enterobacter Prostatitis, Enterococcus Prostatitis, Enterococcus Urinary Tract Infection, Escherichia coli urinary tract infection, Morganella Morganii Urinary Tract Infection, Prostatitis and Proteus Prostatitis and others.

How does Carbenicillin work?

Its molecular targets in DrugCentral include CHRM1, CHRM3, pbpA and mrcA|mrcB|dacC|mrdA|ftsI|dacA|dacB (inhibitor).

What drug class does Carbenicillin belong to?

Carbenicillin is in the Penicillin-class Antibacterial class.

What is the chemical formula of Carbenicillin?

Carbenicillin has the molecular formula C17H18N2O6S and a molecular weight of 378.40 g/mol.

Sources

• DrugCentral drug card 492 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1214 — compound record and bioactivity
• PubChem CID 20824 — chemical identifiers
• DrugBank DB00578 — drug record
• FDA UNII G42ZU72N5G — substance identity
• DailyMed: FDA labels for Carbenicillin — current prescribing information (label search)
• UniProt P11229 (CHRM1) — target protein
• UniProt P20309 (CHRM3) — target protein

How this page is built: methodology · editorial policy & corrections.