Benzalkonium

DERMATOLOGICALS

Key facts

Benzalkonium is a drug catalogued in DrugCentral. Recorded indications include Allergic otitis externa, Itching of ear, Itching of skin and Local anesthesia.

• Indications: Allergic otitis externa, Itching of ear, Itching of skin, Local anesthesia and Minor Skin Wound Pain and others.
• ATC code: D08AJ01 (Quaternary ammonium compounds).
• Molecular formula: C21H38N+; molecular weight 304.54 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (12)

• Allergic otitis externa
• Itching of ear
• Itching of skin
• Local anesthesia
• Minor Skin Wound Pain
• Mouth Irritation
• Otitis externa
• Post-Op Ocular Inflammation
• Prevent Minor Bacterial Skin Infection
• Skin irritation
• Suppression of the Gag Reflex
• Uveitis

Contraindications (21)

• Anemia due to enzyme deficiency
• Bacterial septicemia
• Blister
• Conduction disorder of the heart
• Condyloma acuminatum
• Decreased respiratory function
• Deficiency of cytochrome-b>5< reductase
• Deficiency of glucose-6-phosphate dehydrogenase
• Denuded skin
• Diabetes mellitus
• Disease of liver
• Heart block
• Hypocupremia
• Infection of skin AND/OR subcutaneous tissue
• Inflammatory dermatosis
• Methemoglobinemia
• Open wound
• Perforation of tympanic membrane
• Peripheral vascular disease
• Seizure disorder
• Shock

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	—

ATC classification

ATC code	Therapeutic hierarchy
D08AJ01	DERMATOLOGICALS › ANTISEPTICS AND DISINFECTANTS › ANTISEPTICS AND DISINFECTANTS › Quaternary ammonium compounds
D09AA05	DERMATOLOGICALS › MEDICATED DRESSINGS › MEDICATED DRESSINGS › Medicated dressings with antiinfectives
D09AA11	DERMATOLOGICALS › MEDICATED DRESSINGS › MEDICATED DRESSINGS › Medicated dressings with antiinfectives
R02AA16	RESPIRATORY SYSTEM › THROAT PREPARATIONS › THROAT PREPARATIONS › Antiseptics

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Completed suicide	9292.6
Drug abuse	8428.4
Toxicity to various agents	8011.9
Local anaesthetic systemic toxicity	2073.8
Cardio-respiratory arrest	1839.7
Intentional overdose	1540.8
Overdose	1329.0
Cardiac arrest	1277.5
Suspected suicide	1188.7
Alcohol interaction	1080.6
Substance use disorder	944.3
Suicide attempt	925.2

Chemical structure

• Molecular formula: C₂₁H₃₈N+
• Molecular weight: 304.54 g/mol
• CAS number: —
• InChIKey: CYDRXTMLKJDRQH-UHFFFAOYSA-N
• PubChem CID: 2330

CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Benzalkonium used for?

DrugCentral lists the following indications for Benzalkonium: Allergic otitis externa, Itching of ear, Itching of skin, Local anesthesia, Minor Skin Wound Pain, Mouth Irritation, Otitis externa and Post-Op Ocular Inflammation and others.

What is the chemical formula of Benzalkonium?

Benzalkonium has the molecular formula C21H38N+ and a molecular weight of 304.54 g/mol.

Sources

• DrugCentral drug card 3017 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1187417 — compound record and bioactivity
• PubChem CID 2330 — chemical identifiers
• DrugBank DB11105 — drug record
• FDA UNII 7N6JUD5X6Y — substance identity
• DailyMed: FDA labels for Benzalkonium — current prescribing information (label search)
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.