Bulevirtide
ANTIINFECTIVES FOR SYSTEMIC USE
Also known as: bulevirtide acetate, hepcludex, myrcludex B
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Bulevirtide is a drug catalogued in DrugCentral. It was first approved by the EMA in 2020. DrugCentral lists 1 molecular target, including SLC10A1. Recorded indications include Chronic infection caused by Hepatitis D virus and Chronic viral hepatitis B with hepatitis D.
- Molecular targets: SLC10A1 (1 listed in DrugCentral).
- Indications: Chronic infection caused by Hepatitis D virus and Chronic viral hepatitis B with hepatitis D.
- ATC code: J05AX28 (Other antivirals).
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (2)
- Chronic infection caused by Hepatitis D virus
- Chronic viral hepatitis B with hepatitis D
Mechanism & targets
Molecular targets (1)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Sodium/bile acid cotransporter | SLC10A1 | inhibitor | IC50 6.49 |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| 2020-07-31 | EMA | — | MYR GmbH | Yes |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
J05AX28 | ANTIINFECTIVES FOR SYSTEMIC USE › ANTIVIRALS FOR SYSTEMIC USE › DIRECT ACTING ANTIVIRALS › Other antivirals |
Chemical structure
| Molecular formula | — |
|---|---|
| Molecular weight | — |
| CAS number | — |
| InChIKey | — |
| PubChem CID | 134687648 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Bulevirtide used for?
DrugCentral lists the following indications for Bulevirtide: Chronic infection caused by Hepatitis D virus and Chronic viral hepatitis B with hepatitis D.
How does Bulevirtide work?
Its molecular targets in DrugCentral include SLC10A1 (inhibitor).
When was Bulevirtide first approved?
Bulevirtide was first approved by the EMA in 2020.
Browse: all drugs starting with B · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 5417 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL4297711 — compound record and bioactivity
- PubChem CID 134687648 — chemical identifiers
- DrugBank DB14853 — drug record
- FDA UNII WKM56H3TLB — substance identity
- UniProt Q14973 (SLC10A1) — target protein
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