Butoconazole
Azole Antifungal — GENITO URINARY SYSTEM AND SEX HORMONES
Also known as: butaconazole, butaconazole nitrate, butoconazole nitrate, femstat
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Butoconazole is an ofp drug in the Azole Antifungal class catalogued in DrugCentral. It was first approved by the FDA in 1995. DrugCentral lists 1 molecular target, including ERG11. Recorded indications include Candidal vulvovaginitis.
- Approval status: ofp (first approved 1995 by the FDA).
- Drug class: Azole Antifungal.
- Molecular targets: ERG11 (1 listed in DrugCentral).
- Indications: Candidal vulvovaginitis.
- ATC code: G01AF15 (Imidazole derivatives).
- Molecular formula: C19H17Cl3N2S; molecular weight 411.79 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- Candidal vulvovaginitis
Mechanism & targets
| Established pharmacologic class | Azole Antifungal |
|---|
Molecular targets (1)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Lanosterol 14-alpha demethylase | ERG11 | inhibitor | — |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| 1995-12-21 | FDA | — | BAYER |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
G01AF15 | GENITO URINARY SYSTEM AND SEX HORMONES › GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS › ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS › Imidazole derivatives |
Chemical structure
| Molecular formula | C19H17Cl3N2S |
|---|---|
| Molecular weight | 411.79 g/mol |
| CAS number | — |
| InChIKey | SWLMUYACZKCSHZ-UHFFFAOYSA-N |
| PubChem CID | 47472 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Butoconazole used for?
DrugCentral lists the following indications for Butoconazole: Candidal vulvovaginitis.
How does Butoconazole work?
Its molecular targets in DrugCentral include ERG11 (inhibitor).
When was Butoconazole first approved?
Butoconazole was first approved by the FDA in 1995.
What drug class does Butoconazole belong to?
Butoconazole is in the Azole Antifungal class.
What is the chemical formula of Butoconazole?
Butoconazole has the molecular formula C19H17Cl3N2S and a molecular weight of 411.79 g/mol.
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Sources
- DrugCentral drug card 450 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL1200398 — compound record and bioactivity
- PubChem CID 47472 — chemical identifiers
- DrugBank DB00639 — drug record
- FDA UNII 0Q771797PH — substance identity
- DailyMed: FDA labels for Butoconazole — current prescribing information (label search)
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