Capreomycin
Antimycobacterial — ANTIINFECTIVES FOR SYSTEMIC USE
Also known as: capastat, capostatin, capreomicin, capreomycin sulfate, capreomycine, capreomycine sulfate, capromycin
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Capreomycin is a drug in the Antimycobacterial class catalogued in DrugCentral. It was first approved by the FDA in 1971. Recorded indications include Acute tuberculosis and Pulmonary tuberculosis.
- Drug class: Antimycobacterial.
- Indications: Acute tuberculosis and Pulmonary tuberculosis.
- ATC code: J04AB30 (Antibiotics).
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (2)
- Acute tuberculosis
- Pulmonary tuberculosis
Contraindications (7)
- Dehydration
- Disease of liver
- Disorder of the 8th Cranial Nerve
- Hearing loss
- Hypokalemia
- Kidney disease
- Neuromuscular block, function
Mechanism & targets
| Established pharmacologic class | Antimycobacterial |
|---|
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| 1971-06-02 | FDA | — | AKORN |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
J04AB30 | ANTIINFECTIVES FOR SYSTEMIC USE › ANTIMYCOBACTERIALS › DRUGS FOR TREATMENT OF TUBERCULOSIS › Antibiotics |
Reported adverse-event signals
Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.
| MedDRA term | LLR |
|---|---|
| Electrocardiogram QT prolonged | 269.6 |
| Drug resistance | 221.5 |
| Hepatotoxicity | 78.9 |
| Neuropathy peripheral | 75.4 |
| Optic neuropathy | 68.5 |
| Hepatitis B | 64.9 |
Chemical structure
| Molecular formula | — |
|---|---|
| Molecular weight | — |
| CAS number | — |
| InChIKey | — |
| PubChem CID | 3000502 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Capreomycin used for?
DrugCentral lists the following indications for Capreomycin: Acute tuberculosis and Pulmonary tuberculosis.
When was Capreomycin first approved?
Capreomycin was first approved by the FDA in 1971.
What drug class does Capreomycin belong to?
Capreomycin is in the Antimycobacterial class.
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Sources
- DrugCentral drug card 3063 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL2218913 — compound record and bioactivity
- PubChem CID 3000502 — chemical identifiers
- DrugBank DB00314 — drug record
- FDA UNII 232HYX66HC — substance identity
- DailyMed: FDA labels for Capreomycin — current prescribing information (label search)
- FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral
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