Casopitant

ALIMENTARY TRACT AND METABOLISM

Key facts

Casopitant is a drug catalogued in DrugCentral. DrugCentral lists 2 molecular targets, including TACR1 and SIGMAR1.

• Molecular targets: TACR1 and SIGMAR1 (2 listed in DrugCentral).
• ATC code: A04AD13 (Other antiemetics).
• Molecular formula: C30H35F7N4O2; molecular weight 616.62 g/mol.

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Substance-P receptor	TACR1	antagonist	Ki 9.90
Sigma non-opioid intracellular receptor 1	SIGMAR1	unknown	Ki 5.53

ATC classification

ATC code	Therapeutic hierarchy
A04AD13	ALIMENTARY TRACT AND METABOLISM › ANTIEMETICS AND ANTINAUSEANTS › ANTIEMETICS AND ANTINAUSEANTS › Other antiemetics

Chemical structure

• Molecular formula: C₃₀H₃₅F₇N₄O₂
• Molecular weight: 616.62 g/mol
• CAS number: 414910-27-3
• InChIKey: XGGTZCKQRWXCHW-WMTVXVAQSA-N
• PubChem CID: 9917021

C[C@@H](N(C)C(=O)N1CC[C@@H](C[C@@H]1C1=C(C)C=C(F)C=C1)N1CCN(CC1)C(C)=O)C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Casopitant work?

Its molecular targets in DrugCentral include TACR1 (antagonist) and SIGMAR1.

What is the chemical formula of Casopitant?

Casopitant has the molecular formula C30H35F7N4O2 and a molecular weight of 616.62 g/mol.

Sources

• DrugCentral drug card 4401 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1672054 — compound record and bioactivity
• PubChem CID 9917021 — chemical identifiers
• DrugBank DB06634 — drug record
• FDA UNII 3B03KPM27L — substance identity
• UniProt P25103 (TACR1) — target protein
• UniProt Q99720 (SIGMAR1) — target protein

How this page is built: methodology · editorial policy & corrections.