Chloropyramine

DERMATOLOGICALS

Key facts

Chloropyramine is a drug catalogued in DrugCentral. DrugCentral lists 1 molecular target, including PTK2.

• Molecular targets: PTK2 (1 listed in DrugCentral).
• ATC code: D04AA09 (Antihistamines for topical use).
• Molecular formula: C16H20ClN3; molecular weight 289.81 g/mol.

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Focal adhesion kinase 1	PTK2	unknown	Kd 6.24

ATC classification

ATC code	Therapeutic hierarchy
D04AA09	DERMATOLOGICALS › ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC. › ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC. › Antihistamines for topical use
R06AC03	RESPIRATORY SYSTEM › ANTIHISTAMINES FOR SYSTEMIC USE › ANTIHISTAMINES FOR SYSTEMIC USE › Substituted ethylene diamines
R06AC53	RESPIRATORY SYSTEM › ANTIHISTAMINES FOR SYSTEMIC USE › ANTIHISTAMINES FOR SYSTEMIC USE › Substituted ethylene diamines

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Vaccination site reaction	89.1
Pleural neoplasm	80.9
Carcinoembryonic antigen	70.5
Carbohydrate antigen 15-3	69.3
Cranial nerve disorder	61.3
Bacteriuria	60.6
Right ventricular dilatation	55.7
Breast disorder	53.2
Body temperature increased	45.8
Thyroid mass	45.5
Erythema	44.3

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Chloropyramine is on its molecule page.

• Molecular formula: C₁₆H₂₀ClN₃
• Molecular weight: 289.81 g/mol
• CAS number: 59-32-5
• InChIKey: ICKFFNBDFNZJSX-UHFFFAOYSA-N
• PubChem CID: 25295

CN(C)CCN(CC1=CC=C(Cl)C=C1)C1=CC=CC=N1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Chloropyramine work?

Its molecular targets in DrugCentral include PTK2.

What is the chemical formula of Chloropyramine?

Chloropyramine has the molecular formula C16H20ClN3 and a molecular weight of 289.81 g/mol.

Sources

• DrugCentral drug card 606 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1194287 — compound record and bioactivity
• PubChem CID 25295 — chemical identifiers
• DrugBank DB08800 — drug record
• FDA UNII 2K3L8O9SOV — substance identity
• UniProt Q05397 (PTK2) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.